ARFGEF3 and PHB2

Number of citations of the paper that reports this interaction (PMID 24051437)
3

Data Source:
BioGRID (affinity chromatography technology, unspecified method)

		ARFGEF3	PHB2
Gene Name		ARFGEF family member 3	prohibitin 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Trans-Golgi Network Integral Component Of Membrane	Nucleus Mitochondrion Mitochondrial Inner Membrane Nuclear Matrix Protein Complex Extracellular Vesicular Exosome
	Molecular Function	ARF Guanyl-nucleotide Exchange Factor Activity	Protein Binding Estrogen Receptor Binding
	Biological Process	Negative Regulation Of Phosphatase Activity Vesicle-mediated Transport Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity	Transcription, DNA-templated Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Transcription, DNA-templated Mammary Gland Branching Involved In Thelarche Mammary Gland Alveolus Development Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: PHB2	19 interactors: AFP AKT1 ARFGEF3 ESR1 EZH2 FHL2 HDAC1 HDAC2 HDAC3 HDAC5 MEF2A MYOD1 NR2F1 NR2F2 PPARG PTMA RNF2 TEAD3 UPF2
Entrez ID		57221	11331
HPRD ID		13845	17843
Ensembl ID		ENSG00000112379	ENSG00000215021
Uniprot IDs		C5NM88 Q5TH69	Q99623
PDB IDs
Enriched GO Terms of Interacting Partners?		Mammary Gland Branching Involved In Thelarche Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Development Of Secondary Female Sexual Characteristics Development Of Secondary Sexual Characteristics Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Mammary Gland Alveolus Development Mammary Gland Lobule Development Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Mammary Gland Duct Morphogenesis Regulation Of Morphogenesis Of A Branching Structure Mammary Gland Morphogenesis Mammary Gland Epithelium Development Negative Regulation Of Epithelial Cell Proliferation Gland Morphogenesis Mammary Gland Development Regulation Of Organ Morphogenesis Branching Morphogenesis Of An Epithelial Tube Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure	Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Histone H4 Deacetylation Organ Development Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Cell Development Histone H3 Deacetylation Response To Organic Cyclic Compound Chromatin Modification Regulation Of Striated Muscle Cell Differentiation Histone Modification Cellular Response To Organic Cyclic Compound Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone H3-K9 Modification Regulation Of RNA Metabolic Process Cellular Response To Organic Substance Chromatin Organization Response To Organic Substance Multicellular Organismal Development Regulation Of Gene Expression Anatomical Structure Development Rhythmic Process Regulation Of Muscle Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process
Tagcloud ?			backgroundidentification caspases conclusionsour delineate elucidating hodgkin hubs imperative interactome interactors inverted lentiviral lymphomagenesis lymphomas manipulate mark mcc methodswe nhl oncogenes parp1 premalignant question resultswe sharp splenic strikingly suppressive traf3
Tagcloud (Difference) ?			backgroundidentification caspases conclusionsour delineate elucidating hodgkin hubs imperative interactome interactors inverted lentiviral lymphomagenesis lymphomas manipulate mark mcc methodswe nhl oncogenes parp1 premalignant question resultswe sharp splenic strikingly suppressive traf3
Tagcloud (Intersection) ?