PHB2 and ARFGEF3

Number of citations of the paper that reports this interaction (PMID 24051437)
3

Data Source:
BioGRID (affinity chromatography technology, unspecified method)

		PHB2	ARFGEF3
Gene Name		prohibitin 2	ARFGEF family member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Nuclear Matrix Protein Complex Extracellular Vesicular Exosome	Trans-Golgi Network Integral Component Of Membrane
	Molecular Function	Protein Binding Estrogen Receptor Binding	ARF Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Transcription, DNA-templated Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Transcription, DNA-templated Mammary Gland Branching Involved In Thelarche Mammary Gland Alveolus Development Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis	Negative Regulation Of Phosphatase Activity Vesicle-mediated Transport Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: AFP AKT1 ARFGEF3 ESR1 EZH2 FHL2 HDAC1 HDAC2 HDAC3 HDAC5 MEF2A MYOD1 NR2F1 NR2F2 PPARG PTMA RNF2 TEAD3 UPF2	1 interactors: PHB2
Entrez ID		11331	57221
HPRD ID		17843	13845
Ensembl ID		ENSG00000215021	ENSG00000112379
Uniprot IDs		Q99623	C5NM88 Q5TH69
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Histone H4 Deacetylation Organ Development Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Cell Development Histone H3 Deacetylation Response To Organic Cyclic Compound Chromatin Modification Regulation Of Striated Muscle Cell Differentiation Histone Modification Cellular Response To Organic Cyclic Compound Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone H3-K9 Modification Regulation Of RNA Metabolic Process Cellular Response To Organic Substance Chromatin Organization Response To Organic Substance Multicellular Organismal Development Regulation Of Gene Expression Anatomical Structure Development Rhythmic Process Regulation Of Muscle Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process	Mammary Gland Branching Involved In Thelarche Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Development Of Secondary Female Sexual Characteristics Development Of Secondary Sexual Characteristics Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Mammary Gland Alveolus Development Mammary Gland Lobule Development Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Mammary Gland Duct Morphogenesis Regulation Of Morphogenesis Of A Branching Structure Mammary Gland Morphogenesis Mammary Gland Epithelium Development Negative Regulation Of Epithelial Cell Proliferation Gland Morphogenesis Mammary Gland Development Regulation Of Organ Morphogenesis Branching Morphogenesis Of An Epithelial Tube Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure
Tagcloud ?		backgroundidentification caspases conclusionsour delineate elucidating hodgkin hubs imperative interactome interactors inverted lentiviral lymphomagenesis lymphomas manipulate mark mcc methodswe nhl oncogenes parp1 premalignant question resultswe sharp splenic strikingly suppressive traf3
Tagcloud (Difference) ?		backgroundidentification caspases conclusionsour delineate elucidating hodgkin hubs imperative interactome interactors inverted lentiviral lymphomagenesis lymphomas manipulate mark mcc methodswe nhl oncogenes parp1 premalignant question resultswe sharp splenic strikingly suppressive traf3
Tagcloud (Intersection) ?