RALGAPA2 and DDI1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RALGAPA2	DDI1
Description		Ral GTPase activating protein catalytic subunit alpha 2	DDI proteasomal shuttling factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Protein Heterodimerization Activity	Aspartic-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity
	Biological Process	Ral Protein Signal Transduction Regulation Of Protein Localization Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Exocyst Localization Activation Of GTPase Activity	Proteolysis Proteasomal Protein Catabolic Process Regulation Of Protein Stability Cellular Response To Hydroxyurea Regulation Of DNA Stability
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS		Cognitive function ( 24684796) Fruit consumption ( 32066663) Height ( 28552196 31562340)	Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: DDI1 RALGAPB	18 interacting genes: ADRM1 CCL28 CYGB DVL2 FAM161B GPANK1 GSK3A KLHL42 MFHAS1 NCCRP1 RALGAPA2 RPP25 SDS TEKT3 TRAF2 UBC UBE2K USP2
Entrez ID		57186	414301
HPRD ID		11135	13128
Ensembl ID		ENSG00000188559	ENSG00000170967
Uniprot IDs		Q2PPJ7	Q8WTU0
PDB IDs			3S8I
Enriched GO Terms of Interacting Partners?		Ral Protein Signal Transduction Regulation Of DNA Stability Cellular Response To Hydroxyurea Response To Hydroxyurea Activation Of GTPase Activity Aspartic-type Endopeptidase Activity	Modification-dependent Protein Catabolic Process Ubiquitin Protein Ligase Binding Proteolysis Involved In Protein Catabolic Process Macromolecule Catabolic Process Catabolic Process Proteolysis Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Regulation Of JNK Cascade Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of UDP-glucose Catabolic Process TORC2 Complex Disassembly Regulation Of Brood Size Outer Acrosomal Membrane Fatty Acid Peroxidase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor
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