GPR42 and SLC30A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPR42	SLC30A3
Description		G protein-coupled receptor 42	solute carrier family 30 member 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cytoplasm Lysosome Lysosomal Membrane Endosome Late Endosome Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Late Endosome Membrane Neuron Projection Synapse Hippocampal Mossy Fiber Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Microvesicle
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Monoatomic Cation Transmembrane Transporter Activity Antiporter Activity Metal Ion Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway	Monoatomic Ion Transport Monoatomic Cation Transport Zinc Ion Transport Response To Zinc Ion Positive Regulation Of Transport Transmembrane Transport Zinc Ion Import Into Organelle Zinc Ion Transmembrane Transport Zinc Ion Import Into Synaptic Vesicle Zinc Ion Import Into Lysosome
Pathways			Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		110 interacting genes: ADGRE2 ADIPOQ ALOX5AP ANKRD46 APOD ATP13A1 ATP4B ATP6V0B ATP6V0C BNIP3 BTN2A2 C1GALT1 CATSPERH CCDC167 CCL4L2 CD300C CD79A CLCA4 CLEC2D CMTM5 COMT CTXN3 CXCL16 CXCL9 DRAM1 EFNA5 EMP1 ERG28 ERMP1 FAM3C FXYD3 FXYD6 GIMAP5 GJB2 GOSR2 GPR37L1 GYPC IER3IP1 IGFBP5 IL1RL1 ITGAM JPH1 KCNA1 KLRG1 LAT LEPROTL1 LHFPL5 LNPEP LTC4S MFSD6 MGAM MS4A1 MS4A13 NDUFB11 NINJ2 NRM NSG1 PAEP PLP1 PLPP1 PMP22 PNLIPRP1 RPRM RTP2 RUSF1 SCD SERINC1 SERP2 SERTM1 SLC30A2 SLC30A3 SLC30A8 SLC35E4 SLC38A1 SLC38A7 SLC39A2 SLC41A1 SLC41A2 SLC61A1 SMCO4 SMIM3 STATH STRIT1 STX8 SYNDIG1 SYNGR1 TEX264 TF TM4SF4 TMBIM6 TMEM128 TMEM140 TMEM147 TMEM182 TMEM19 TMEM237 TMEM239 TMEM242 TMEM30B TMEM60 TMEM65 TRARG1 TREX1 TSPO2 YIF1A YIPF1 YIPF2 YIPF4 YIPF6 ZFPL1	33 interacting genes: AP3B1 AP3D1 AP3S1 AQP6 CD40 CD79A CGRRF1 CYB5R3 DNAJC5 ELOVL4 FCRL3 FKBP7 GJA8 GOLM1 GPR152 GPR42 GPX8 HSD17B13 LMNA NAALADL2 RETREG3 RNF19B RTN3 SAR1A SCN3B SGPL1 SLC10A6 SLC18A1 SLC30A8 SLC34A2 SLC35H1 TMEM14B TMEM242
Entrez ID		2866	7781
HPRD ID		16033	11924
Ensembl ID		ENSG00000126251	ENSG00000115194
Uniprot IDs		A0A0K0PUY3 O15529	B4DXX8 Q99726
PDB IDs			8XN1
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Monoatomic Ion Transport Monoatomic Cation Transmembrane Transporter Activity Protein Binding Metal Ion Transport Monoatomic Cation Transport Endoplasmic Reticulum Inorganic Ion Transmembrane Transport Transmembrane Transport Endoplasmic Reticulum Membrane Monoatomic Ion Transmembrane Transport Inorganic Cation Transmembrane Transport Monoatomic Cation Transmembrane Transport Zinc Ion Transmembrane Transporter Activity Golgi Trans Cisterna Zinc Ion Transmembrane Transport Golgi Medial Cisterna Zinc Ion Transport Zinc Ion Import Into Organelle Monoatomic Cation Homeostasis Zinc Ion Import Into Lysosome Intracellular Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Intracellular Monoatomic Ion Homeostasis Leukotriene-C4 Synthase Activity Chemical Homeostasis Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Zinc:proton Antiporter Activity Cellular Response To Magnesium Ion	Membrane Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Vesicle Cargo Loading AP-3 Adaptor Complex Anterograde Synaptic Vesicle Transport Melanosome Assembly Platelet Dense Granule Organization Membrane Coat Positive Regulation Of NK T Cell Differentiation Synaptic Vesicle Transport Synaptic Vesicle Coating Vesicle Coating Melanosome Organization Pigment Granule Organization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Regulation Of NK T Cell Differentiation Anterograde Axonal Transport Endoplasmic Reticulum Vesicle Transport Along Microtubule Zinc Ion Import Into Organelle Vesicle Cytoskeletal Trafficking Transmembrane Transport Axon Cytoplasm Axonal Transport Secretory Granule Organization Protein Binding Synaptic Vesicle Recycling Axo-dendritic Transport Golgi To Vacuole Transport Organelle Transport Along Microtubule Endoplasmic Reticulum Membrane Endoplasmic Reticulum Tubular Network Organization Inorganic Cation Transmembrane Transport Presynapse Establishment Of Vesicle Localization Zinc Ion Transmembrane Transport Zinc Ion Transport Monoatomic Ion Transport Vesicle Localization Intracellular Zinc Ion Homeostasis Establishment Of Organelle Localization Nitrate Transmembrane Transporter Activity Inorganic Ion Transmembrane Transport Sphinganine-1-phosphate Aldolase Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport
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