RHBG and SH2B1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RHBG	SH2B1
Gene Name		Rh family, B glycoprotein (gene/pseudogene)	SH2B adaptor protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Spectrin-associated Cytoskeleton Basolateral Plasma Membrane Cytoplasmic Vesicle Membrane Anchored Component Of Plasma Membrane	Nucleus Cytosol Membrane
	Molecular Function	Ammonium Transmembrane Transporter Activity Ankyrin Binding	Signal Transducer Activity Protein Binding
	Biological Process	Ammonium Transport Transmembrane Transport Transepithelial Ammonium Transport Ammonium Transmembrane Transport	Movement Of Cell Or Subcellular Component Blood Coagulation Lamellipodium Assembly Intracellular Signal Transduction Positive Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process
Pathways		Rhesus glycoproteins mediate ammonium transport. Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds SLC-mediated transmembrane transport	Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Subcutaneous adipose tissue ( 22589738) Visceral adipose tissue adjusted for BMI ( 22589738)	Body mass index ( 19079260 19079261 20935630) Crohn's disease ( 21102463) Obesity ( 23563607) Weight ( 19079260)
Protein-Protein Interactions		1 interactors: SH2B1	12 interactors: EGFR FGFR3 GRB2 IGF1R INSR IRS1 JAK2 KIAA0319 NTRK1 NTRK2 RHBG SH2B2
Entrez ID		57127	25970
HPRD ID		06152	12336
Ensembl ID		ENSG00000132677	ENSG00000178188
Uniprot IDs		Q9H310	B3KNV5 B4DLN5 F5GXU7 Q9NRF2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process Lamellipodium Assembly Lamellipodium Organization Positive Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Nuclear Division Positive Regulation Of Cell Division Positive Regulation Of Cell Cycle Process Regulation Of Cell Division Positive Regulation Of Cell Cycle Cell Projection Assembly	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organonitrogen Compound Enzyme Linked Receptor Protein Signaling Pathway Protein Autophosphorylation Positive Regulation Of Signal Transduction Response To Organonitrogen Compound Peptidyl-tyrosine Phosphorylation Phosphatidylinositol-mediated Signaling Cellular Response To Peptide Hormone Stimulus Insulin Receptor Signaling Pathway Cellular Response To Hormone Stimulus Cellular Response To Peptide Regulation Of MAPK Cascade Cellular Response To Insulin Stimulus Neurotrophin TRK Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of MAPK Cascade Cellular Response To Organic Substance Neurotrophin Signaling Pathway Response To Peptide Hormone Regulation Of Phosphorylation Response To Peptide Positive Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Response To Hormone Response To Insulin Cellular Response To Growth Factor Stimulus Response To Growth Factor Response To Organic Substance Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Proliferation System Development Positive Regulation Of Kinase Activity Regulation Of Signaling Positive Regulation Of Reactive Oxygen Species Metabolic Process Cell Surface Receptor Signaling Pathway Regulation Of Cell Proliferation Peptidyl-amino Acid Modification Neuron Development Nervous System Development Generation Of Neurons Positive Regulation Of Transferase Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Axon Development Multicellular Organismal Development Neurogenesis Regulation Of Protein Phosphorylation
Tagcloud ?		ae ammonium anchoring ankyrin band basolateral bilayer biosynthesis challenge constitutes emerging erythroid gpc member membrane mutated next null observations p55 polarized red rhag similarly skeleton spectrin summarize weak	actin adapter branching depends enhance enhances fact filopoda filopodia filopodium formation hippocampal initiation insoluble interacts irsp53 isoform localize neurite neurons outgrowth overexpressing predominant prerequisite proline regulate rich triton
Tagcloud (Difference) ?		ae ammonium anchoring ankyrin band basolateral bilayer biosynthesis challenge constitutes emerging erythroid gpc member membrane mutated next null observations p55 polarized red rhag similarly skeleton spectrin summarize weak	actin adapter branching depends enhance enhances fact filopoda filopodia filopodium formation hippocampal initiation insoluble interacts irsp53 isoform localize neurite neurons outgrowth overexpressing predominant prerequisite proline regulate rich triton
Tagcloud (Intersection) ?