PCBP4 and RNF138

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PCBP4	RNF138
Description		poly(rC) binding protein 4	ring finger protein 138
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ribonucleoprotein Complex	Nucleus Chromosome Site Of Double-strand Break
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding	DNA Binding Single-stranded DNA Binding Protein Binding Zinc Ion Binding Transferase Activity Protein Kinase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of MRNA Stability Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Damage Response DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Wnt Signaling Pathway Protein Ubiquitination Cellular Response To Leukemia Inhibitory Factor
Pathways		TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Transcriptional activation of cell cycle inhibitor p21 FOXO-mediated transcription of cell cycle genes	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: LYST PCBP1 QKI RBFOX1 RNF138 WBP11	18 interacting genes: APP CFAP206 EFEMP2 H3C1 LNX2 NTAQ1 PCBP4 QKI RAD51D TAF9 TCF7L2 TP53 TRIM8 UBC UBE2D2 UBE2D4 UBE2K UBE2W
Entrez ID		57060	51444
HPRD ID		16343	11508
Ensembl ID		ENSG00000090097	ENSG00000134758
Uniprot IDs		C9J0A4 P57723	A0A140VJT9 Q8WVD3
PDB IDs
Enriched GO Terms of Interacting Partners?		Single-stranded DNA Binding Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process MRNA Binding RNA Splicing Internal N(7)-methylguanine-containing RNA Reader Activity Mast Cell Secretory Granule Organization Sequence-specific Single Stranded DNA Binding Myofibroblast Contraction Cytoplasmic Stress Granule MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MiRNA Catabolic Process Nucleic Acid Binding Regulation Of MRNA Processing Spliceosome-depend Formation Of Circular RNA MRNA Metabolic Process RNA Transport RNA Binding Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Viral RNA Genome Replication Macromolecule Metabolic Process Regulation Of RNA Splicing Microglia Differentiation Negative Regulation Of Macrophage Differentiation Nucleobase-containing Compound Transport Negative Regulation Of 3'-UTR-mediated MRNA Stabilization DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Nuclear Stress Granule RNA Processing Vascular Associated Smooth Muscle Cell Differentiation	Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Protein Polyubiquitination Macromolecule Metabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Nucleus Regulation Of MiRNA Metabolic Process Post-translational Protein Modification Protein K48-linked Ubiquitination PML Body Modification-dependent Protein Catabolic Process Ubiquitin Protein Ligase Binding Regulation Of Small Molecule Metabolic Process Molecular Function Activator Activity MRNA 3'-UTR Binding Protein Heterodimerization Activity Replication Fork Chromosome Organization Regulation Of Protein Localization To Nucleus Proteolysis Involved In Protein Catabolic Process Regulation Of Proteolysis Amyloid-beta Complex Growth Cone Lamellipodium DNA Binding Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Toll Signaling Pathway Regulation Of Apoptotic Signaling Pathway Protein Modification Process Regulation Of RNA Splicing Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Internal N(7)-methylguanine-containing RNA Reader Activity Positive Regulation Of Smooth Muscle Cell-matrix Adhesion Protein K11-linked Ubiquitination Protein-N-terminal Glutamine Amidohydrolase Activity A Axonemal Microtubule Acetylcholine Receptor Activator Activity Positive Regulation Of Gene Expression, Epigenetic PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Epigenetic Regulation Of Gene Expression Positive Regulation Of Neuron Apoptotic Process Regulation Of Carbohydrate Catabolic Process Regulation Of MiRNA Transcription Endosome To Plasma Membrane Transport Vesicle
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