PCBP4 and WBP11

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		PCBP4	WBP11
Description		poly(rC) binding protein 4	WW domain binding protein 11
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding	Single-stranded DNA Binding RNA Binding Protein Binding WW Domain Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of MRNA Stability Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process	RRNA Processing RNA Processing MRNA Processing RNA Splicing
Pathways		TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Transcriptional activation of cell cycle inhibitor p21 FOXO-mediated transcription of cell cycle genes	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		6 interacting genes: LYST PCBP1 QKI RBFOX1 RNF138 WBP11	37 interacting genes: APBB1 ARF1 C5orf22 CD2BP2 CEBPA CTNNBL1 DDX17 DDX5 FOXP1 FYN GIGYF2 GRB2 ITSN1 MCRS1 MORN4 NCK2 NOD2 PCBP4 PIK3R1 PPP1CA PPP1CB PPP1CC PQBP1 PRMT2 PRPF40A RBM5 RSPH1 RTN4IP1 RUNX1T1 SEC23A SRC TESC TRAF4 TRIP10 UBASH3A VIM WBP4
Entrez ID		57060	51729
HPRD ID		16343	18293
Ensembl ID		ENSG00000090097	ENSG00000084463
Uniprot IDs		C9J0A4 P57723	Q9Y2W2
PDB IDs			7ABF 7ABG
Enriched GO Terms of Interacting Partners?		Single-stranded DNA Binding Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process MRNA Binding RNA Splicing Internal N(7)-methylguanine-containing RNA Reader Activity Mast Cell Secretory Granule Organization Sequence-specific Single Stranded DNA Binding Myofibroblast Contraction Cytoplasmic Stress Granule MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MiRNA Catabolic Process Nucleic Acid Binding Regulation Of MRNA Processing Spliceosome-depend Formation Of Circular RNA MRNA Metabolic Process RNA Transport RNA Binding Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Viral RNA Genome Replication Macromolecule Metabolic Process Regulation Of RNA Splicing Microglia Differentiation Negative Regulation Of Macrophage Differentiation Nucleobase-containing Compound Transport Negative Regulation Of 3'-UTR-mediated MRNA Stabilization DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Nuclear Stress Granule RNA Processing Vascular Associated Smooth Muscle Cell Differentiation	Nuclear Speck Proline-rich Region Binding Cytosol RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome PTW/PP1 Phosphatase Complex Nucleus RNA Splicing Ribonucleoprotein Complex Binding Cytoplasm Regulation Of RNA Splicing Nucleoplasm MRNA Processing Protein Domain Specific Binding Regulation Of Defense Response Protein-containing Complex Binding Regulation Of Gene Expression Scaffold Protein Binding Entrainment Of Circadian Clock By Photoperiod Alternative MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Nuclear Androgen Receptor Binding Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Ephrin Receptor Binding Photoperiodism Entrainment Of Circadian Clock Regulation Of RNA Metabolic Process Regulation Of Apoptotic Process MRNA Metabolic Process Regulation Of Innate Immune Response Regulation Of Programmed Cell Death Positive Regulation Of Immune System Process Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Regulation Of Macromolecule Metabolic Process Neurotrophin TRKA Receptor Binding Regulation Of MRNA Metabolic Process Regulation Of Caveolin-mediated Endocytosis Osteoclast Development Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Regulation Of Developmental Process Regulation Of Immune System Process Regulation Of MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Signal Complex Assembly T Cell Costimulation
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