RXRG and NR0B2

Number of citations of the paper that reports this interaction (PMID 8650544)
88

Data Source:
BioGRID (pull down)

		RXRG	NR0B2
Gene Name		retinoid X receptor, gamma	nuclear receptor subfamily 0, group B, member 2
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Protein Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Steroid Hormone Receptor Activity 9-cis Retinoic Acid Receptor Activity Protein Binding Zinc Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Protein Complex Binding Protein Homodimerization Activity Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Peripheral Nervous System Development Heart Development Skeletal Muscle Tissue Development Gene Expression Neuron Differentiation Regulation Of Myelination Response To Retinoic Acid Steroid Hormone Mediated Signaling Pathway Retinoic Acid Receptor Signaling Pathway Protein Homotetramerization Transmembrane Transport Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cholesterol Metabolic Process Response To Glucose Gene Expression Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Organ Regeneration Positive Regulation Of Insulin Secretion Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways		Generic Transcription Pathway Signaling by Retinoic Acid Nuclear Receptor transcription pathway Orphan transporters	Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs		Adapalene Bexarotene Acitretin Alitretinoin Tretinoin Etretinate
Diseases
GWAS		AIDS ( 19754311) Menarche (age at onset) ( 21102462) Personality dimensions ( 21368711)
Protein-Protein Interactions		29 interactors: CAMK2B CEBPZ CHGB CREBBP DCK HOXD4 ITGB3BP LRSAM1 MAP4 MPPED2 NCOA6 NCOR2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR4A1 PNO1 PPARA PPARD PPARG RARA RARB RARG SRF THRA THRB VDR	46 interactors: AR CHRD DDX20 EID1 ESR1 ESR2 ESRRA ESRRG FN1 GPS2 HDAC3 HDAC6 HNF4A HNF4G HNRNPA1 IL3RA NCOA3 NR1H2 NR1H3 NR1I3 NR5A2 PAX9 PEF1 PLSCR1 POLR2A PPARD PPARG RARA RARG RBP5 RNF31 RXRA RXRB RXRG SMAD4 SMARCA2 SMARCB1 SMARCE1 SNW1 THRA TP53 UBC VDR XBP1 ZAP70 ZMYND10
Entrez ID		6258	8431
HPRD ID		01579	05219
Ensembl ID		ENSG00000143171	ENSG00000131910
Uniprot IDs		F1D8Q7 F1T097 P48443	Q15466
PDB IDs		2GL8	1YUC 2Q3Y 2Z4J 4DOR
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Response To Steroid Hormone Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Hormone Transcription, DNA-templated RNA Biosynthetic Process Cellular Response To Hormone Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Response To Lipid Positive Regulation Of Transcription, DNA-templated Response To Organic Cyclic Compound Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Organic Substance Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Organic Substance Gene Expression Cellular Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cholesterol Storage Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process	Transcription Initiation From RNA Polymerase II Promoter Steroid Hormone Mediated Signaling Pathway Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Lipid Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Response To Organic Cyclic Compound Cellular Response To Hormone Stimulus RNA Metabolic Process Response To Steroid Hormone Regulation Of Transcription, DNA-templated Cellular Response To Organic Substance Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Response To Lipid Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Response To Organic Substance Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Hormone Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Retinoic Acid Receptor Signaling Pathway Response To Organic Cyclic Compound Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Biosynthetic Process
Tagcloud ?		band bands chromosome chromosomes cosmid cosmids cytogenetic encoded establishing heterodimeric location loci pairwise partners proximity q22 q23 q34 reference respond retinoic retinoid rxra rxrb rxrs separate tr vdr	abolished adenovirus ag490 amp ataxia atm carboxykinase gh gluconeogenesis hepatic hepatocytes heterodimer interacted ku mediating metformin null orphan partner pepck phosphatidylinositol phosphoenolpyruvate physically pivotal regulating shp stat5 superfamily telangiectasia
Tagcloud (Difference) ?		band bands chromosome chromosomes cosmid cosmids cytogenetic encoded establishing heterodimeric location loci pairwise partners proximity q22 q23 q34 reference respond retinoic retinoid rxra rxrb rxrs separate tr vdr	abolished adenovirus ag490 amp ataxia atm carboxykinase gh gluconeogenesis hepatic hepatocytes heterodimer interacted ku mediating metformin null orphan partner pepck phosphatidylinositol phosphoenolpyruvate physically pivotal regulating shp stat5 superfamily telangiectasia
Tagcloud (Intersection) ?