COXFA4L2 and EIF3C

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		COXFA4L2	EIF3C
Name		cytochrome c oxidase hypoxia associated subunit FA4L2	eukaryotic translation initiation factor 3 subunit C
Structure		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Respiratory Chain Complex IV	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex
	Molecular Function	None	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Initiation Factor Binding Ribosome Binding
	Biological Process	None	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Translation Translational Initiation Positive Regulation Of Translation
Pathways		None	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs		NADH	None
GWAS		No GWAS studies recorded	Brain morphology (MOSTest) ( 32665545 ) Crohn's disease ( 21102463 28067908 ) Extremely high intelligence ( 29520040 ) Inflammatory bowel disease ( 23128233 28067908 ) Inflammatory bowel disease (early onset) ( 19915574 ) Lamb consumption ( 32066663 )
Interacting Genes		14 interacting genes: ANXA9 C6orf62 COMMD8 DYNLL1 EIF3C ERG28 KAT5 KCNA4 LUC7L2 NUFIP2 PRKN QTRT1 SLC35F6 UBR1	23 interacting genes: AAGAB ALKBH4 BTG3 CALM1 COXFA4L2 DSCAM EIF1AX EIF3E EIF3G EIF3J EIF3K ERCC6 HMOX2 MAPK6 PFDN1 PLEKHF2 RNF10 RPS6KA3 SMAD9 SNCA SNIP1 TACC3 TRAPPC2
Entrez ID		56901	8663
HPRD ID		14249	04889
Ensembl ID		ENSG00000185633	ENSG00000184110
Uniprot IDs		Q9NRX3	Q99613
PDB IDs		Not available	3J8B 3J8C 6YBD 6YBW 6ZMW 6ZON 6ZP4 7A09 7QP6 7QP7 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPL 8RG0 8XXN 9BLN
GO Terms Enriched among Interactors		None	Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Formation Of Cytoplasmic Translation Initiation Complex Eukaryotic Translation Initiation Factor 3 Complex Translation Initiation Factor Activity Translational Initiation Cytoplasmic Translational Initiation Protein-RNA Complex Assembly Regulation Of Acyl-CoA Biosynthetic Process Translation Vesicle-mediated Transport In Synapse Positive Regulation Of Vesicle Fusion