TMEM167B and CD47

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM167B	CD47
Description		transmembrane protein 167B	CD47 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Plasma Membrane Cell Surface Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Protein Binding	Protein Binding Fibrinogen Binding Thrombospondin Receptor Activity Protein Binding Involved In Heterotypic Cell-cell Adhesion Cell-cell Adhesion Mediator Activity
	Biological Process	Constitutive Secretory Pathway	Angiogenesis Positive Regulation Of Immune System Process Apoptotic Process Inflammatory Response Cell Adhesion Integrin-mediated Signaling Pathway Positive Regulation Of Cell Population Proliferation Cell Migration Positive Regulation Of Cell-cell Adhesion Regulation Of Type II Interferon Production Regulation Of Interleukin-10 Production Regulation Of Interleukin-12 Production Regulation Of Interleukin-6 Production Regulation Of Tumor Necrosis Factor Production Heterotypic Cell-cell Adhesion Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Inflammatory Response Negative Regulation Of Phagocytosis Positive Regulation Of Phagocytosis Positive Regulation Of T Cell Activation Positive Regulation Of Stress Fiber Assembly Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Type II Interferon Cellular Response To Interleukin-1 Cellular Response To Interleukin-12 Cell-cell Adhesion ATP Export Positive Regulation Of Monocyte Extravasation
Pathways			Cell surface interactions at the vascular wall Integrin cell surface interactions Signal regulatory protein family interactions Signal regulatory protein family interactions Neutrophil degranulation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301)	Bipolar disorder ( 31043756 33263727 34002096) Body mass index ( 25673413) Refractive error ( 32231278) Regular attendance at a religious group ( 29970889)
Interacting Genes		33 interacting genes: ACKR2 AGPAT3 APOL3 AQP10 AQP6 ASPH C14orf180 CD300C CD47 CTXN3 EBP FXYD6-FXYD2 HSD17B11 HSD17B13 LETMD1 LSS MGST2 PLLP REEP4 SACM1L SEC22B SERINC2 SLC34A3 SLC71A2 SMPD2 STX12 STX1B TAS2R19 TM4SF19 TMEM100 TMEM107 UNC50 ZDHHC21	17 interacting genes: BNIP3 EPB42 FAS GNAI1 ITGAV MTIF3 MUC1 P2RY2 PTK2 PVR RHAG SIRPA SRC SYNE4 THBS1 TMEM167B UBQLN1
Entrez ID		56900	961
HPRD ID		16474	03017
Ensembl ID		ENSG00000215717	ENSG00000196776
Uniprot IDs		A0A494C0V7 Q9NRX6	A0A0A1TSG4 Q08722
PDB IDs			2JJS 2JJT 2VSC 4CMM 4KJY 5IWL 5TZ2 5TZT 5TZU 7MYZ 7WN8 7XJF 7YGG 8RP8
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Steroid Dehydrogenase Activity Lipid Droplet SNAP Receptor Activity Lipid Metabolic Process Water Channel Activity Lipid Biosynthetic Process Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity	Response To Mechanical Stimulus Regulation Of Apoptotic Signaling Pathway Cellular Response To Stress Signaling Receptor Activity Ankyrin-1 Complex Integrin Binding Signal Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Catabolic Process Cellular Response To Hydrogen Peroxide Positive Regulation Of Phosphate Metabolic Process Regulation Of Focal Adhesion Assembly Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Cell-substrate Junction Organization Regulation Of Proteolysis Negative Regulation Of Programmed Cell Death Positive Regulation Of Fibroblast Migration Positive Regulation Of Metabolic Process Response To Hyperoxia Response To Hydrogen Peroxide Filopodium Membrane Negative Regulation Of Transport Transforming Growth Factor Beta Binding Fibroblast Growth Factor Binding Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Integrin-mediated Signaling Pathway Positive Regulation Of Phosphorylation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Macrophage Chemotaxis Negative Regulation Of Anoikis Negative Regulation Of Focal Adhesion Assembly Positive Regulation Of Glycolytic Process Cellular Response To Reactive Oxygen Species Cell Motility Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Chemical Stress Multicellular Organismal-level Iron Ion Homeostasis Symbiont Entry Into Host Cell Protein Autophosphorylation Positive Regulation Of Macrophage Migration Regulation Of Anoikis Autophagy Fibronectin Binding Regulation Of Cell Adhesion Extracellular Matrix Binding Regulation Of Cell-matrix Adhesion
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