TMEM167B and SLC34A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM167B	SLC34A3
Description		transmembrane protein 167B	solute carrier family 34 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Plasma Membrane Brush Border Membrane Apical Plasma Membrane Brush Border Membrane Vesicle
	Molecular Function	Protein Binding	Sodium:phosphate Symporter Activity Protein Binding Symporter Activity
	Biological Process	Constitutive Secretory Pathway	Monoatomic Ion Transport Sodium Ion Transport Phosphate Ion Transport Intracellular Phosphate Ion Homeostasis Sodium Ion Transmembrane Transport Sodium-dependent Phosphate Transport Transmembrane Transport
Pathways			Type II Na+/Pi cotransporters Defective SLC34A3 causes Hereditary hypophosphatemic rickets with hypercalciuria (HHRH)
Drugs
Diseases			Hypophosphatemic rickets; X-Linked dominant hypophosphatemia (XLH); Autosomal dominant hypophosphatemic rickets (ADHR); Autosomal recessive hypophosphatemic rickets (ARHR); Hereditary hypophophatemic rickets with hypercalciuria (HHRH)
GWAS		Apolipoprotein B levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		33 interacting genes: ACKR2 AGPAT3 APOL3 AQP10 AQP6 ASPH C14orf180 CD300C CD47 CTXN3 EBP FXYD6-FXYD2 HSD17B11 HSD17B13 LETMD1 LSS MGST2 PLLP REEP4 SACM1L SEC22B SERINC2 SLC34A3 SLC71A2 SMPD2 STX12 STX1B TAS2R19 TM4SF19 TMEM100 TMEM107 UNC50 ZDHHC21	4 interacting genes: CLRN1 GPX8 TMEM167B TMEM234
Entrez ID		56900	142680
HPRD ID		16474	10236
Ensembl ID		ENSG00000215717	ENSG00000198569
Uniprot IDs		A0A494C0V7 Q9NRX6	Q8N130
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Steroid Dehydrogenase Activity Lipid Droplet SNAP Receptor Activity Lipid Metabolic Process Water Channel Activity Lipid Biosynthetic Process Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity	Equilibrioception Regulation Of Ribosome Biogenesis Positive Regulation Of Translational Elongation Mitotic Nuclear Division Positive Regulation Of Ribosome Biogenesis Histone H2A Deubiquitinase Activity Mitochondrial Ribosome Assembly Constitutive Secretory Pathway
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