TMEM167B and AGPAT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM167B	AGPAT3
Description		transmembrane protein 167B	1-acylglycerol-3-phosphate O-acyltransferase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Golgi Membrane Nucleus Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Endomembrane System Membrane
	Molecular Function	Protein Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Lysophosphatidic Acid Acyltransferase Activity
	Biological Process	Constitutive Secretory Pathway	Lipid Metabolic Process Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process
Pathways			Synthesis of PA COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301)	Adverse response to drug ( 30420678) Estimated glomerular filtration rate in diabetes ( 31451708) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377)
Interacting Genes		33 interacting genes: ACKR2 AGPAT3 APOL3 AQP10 AQP6 ASPH C14orf180 CD300C CD47 CTXN3 EBP FXYD6-FXYD2 HSD17B11 HSD17B13 LETMD1 LSS MGST2 PLLP REEP4 SACM1L SEC22B SERINC2 SLC34A3 SLC71A2 SMPD2 STX12 STX1B TAS2R19 TM4SF19 TMEM100 TMEM107 UNC50 ZDHHC21	19 interacting genes: ABHD16A APP AQP6 BNIP2 CREB3 CREB3L1 FAM133A GOLT1A HSD17B11 HSD17B13 MPP1 NKAPD1 SLC10A1 SLC35H1 SLC71A2 SREK1IP1 TMEM14B TMEM167B TMX2
Entrez ID		56900	56894
HPRD ID		16474	10637
Ensembl ID		ENSG00000215717	ENSG00000160216
Uniprot IDs		A0A494C0V7 Q9NRX6	Q9NRZ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Steroid Dehydrogenase Activity Lipid Droplet SNAP Receptor Activity Lipid Metabolic Process Water Channel Activity Lipid Biosynthetic Process Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity	Steroid Dehydrogenase Activity Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Positive Regulation Of Monocyte Chemotaxis Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
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