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CD47 and FAS
Number of citations of the paper that reports this interaction (PubMedID
15917238
)
0
Data Source:
HPRD
(in vitro)
CD47
FAS
Description
CD47 molecule
Fas cell surface death receptor
Image
GO Annotations
Cellular Component
Plasma Membrane
Cell Surface
Membrane
Specific Granule Membrane
Extracellular Exosome
Tertiary Granule Membrane
Extracellular Region
Cytosol
Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Membrane
Nuclear Body
Death-inducing Signaling Complex
CD95 Death-inducing Signaling Complex
Membrane Raft
Extracellular Exosome
Molecular Function
Protein Binding
Fibrinogen Binding
Thrombospondin Receptor Activity
Protein Binding Involved In Heterotypic Cell-cell Adhesion
Cell-cell Adhesion Mediator Activity
Transmembrane Signaling Receptor Activity
Tumor Necrosis Factor Receptor Activity
Protein Binding
Calmodulin Binding
Kinase Binding
Signaling Receptor Activity
Identical Protein Binding
Biological Process
Angiogenesis
Positive Regulation Of Immune System Process
Apoptotic Process
Inflammatory Response
Cell Adhesion
Integrin-mediated Signaling Pathway
Positive Regulation Of Cell Population Proliferation
Cell Migration
Positive Regulation Of Cell-cell Adhesion
Regulation Of Type II Interferon Production
Regulation Of Interleukin-10 Production
Regulation Of Interleukin-12 Production
Regulation Of Interleukin-6 Production
Regulation Of Tumor Necrosis Factor Production
Heterotypic Cell-cell Adhesion
Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Inflammatory Response
Negative Regulation Of Phagocytosis
Positive Regulation Of Phagocytosis
Positive Regulation Of T Cell Activation
Positive Regulation Of Stress Fiber Assembly
Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
Cellular Response To Type II Interferon
Cellular Response To Interleukin-1
Cellular Response To Interleukin-12
Cell-cell Adhesion
ATP Export
Positive Regulation Of Monocyte Extravasation
Apoptotic Process
Activation-induced Cell Death Of T Cells
Immune Response
Signal Transduction
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Stress-activated MAPK Cascade
Tumor Necrosis Factor-mediated Signaling Pathway
Cellular Response To Amino Acid Starvation
Fas Signaling Pathway
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Protein-containing Complex Assembly
Cellular Response To Mechanical Stimulus
Cellular Response To Hyperoxia
Motor Neuron Apoptotic Process
Extrinsic Apoptotic Signaling Pathway
Necroptotic Signaling Pathway
Positive Regulation Of Reactive Oxygen Species Biosynthetic Process
Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Signal regulatory protein family interactions
Signal regulatory protein family interactions
Neutrophil degranulation
Caspase activation via Death Receptors in the presence of ligand
Regulation by c-FLIP
RIPK1-mediated regulated necrosis
CASP8 activity is inhibited
TP53 Regulates Transcription of Death Receptors and Ligands
Dimerization of procaspase-8
FasL/ CD95L signaling
Drugs
Diseases
Esophageal cancer
Chronic lymphocytic leukemia (CLL)
Hodgkin lymphoma
Adult T-cell leukemia
GWAS
Bipolar disorder (
31043756
33263727
34002096
)
Body mass index (
25673413
)
Refractive error (
32231278
)
Regular attendance at a religious group (
29970889
)
Ankylosing spondylitis (
30946743
)
Atrioventricular conduction (
21041692
)
Blood protein levels (
30072576
)
Blood protein levels in cardiovascular risk (
28369058
)
Chronic lymphocytic leukemia (
23770605
24292274
26956414
28165464
)
Immunoglobulin A (
20694011
)
Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) (
23603761
)
Mean corpuscular volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Mosquito bite size (
28199695
)
Obesity-related traits (
23251661
)
Red blood cell count (
32888494
)
Selective IgA deficiency (
27723758
)
Interacting Genes
17 interacting genes:
BNIP3
EPB42
FAS
GNAI1
ITGAV
MTIF3
MUC1
P2RY2
PTK2
PVR
RHAG
SIRPA
SRC
SYNE4
THBS1
TMEM167B
UBQLN1
50 interacting genes:
ANK3
APAF1
APOA5
ATP6V0B
BAG6
BTK
CALM1
CASP8
CASP8AP2
CCND3
CD47
CRMP1
DAXX
DNAJC5
EEF1A1
EGFR
ERG28
EZR
FADD
FAF1
FAF2
FAIM2
FASLG
FBF1
FEM1B
FYN
GADD45A
HIPK3
HNRNPC
LCK
LRIF1
MBD4
MET
PDCD6
PRKCA
PTPN13
PTPN6
RAP1A
RIPK1
SUMO1
TCAP
TMX1
TNFSF13
TRADD
TRAF3
TRIP6
UBA7
UBAC1
UBE2I
UBQLN1
Entrez ID
961
355
HPRD ID
03017
00609
Ensembl ID
ENSG00000196776
ENSG00000026103
Uniprot IDs
A0A0A1TSG4
Q08722
A0A8Q3SIR6
K9J972
P25445
Q59FU8
PDB IDs
2JJS
2JJT
2VSC
4CMM
4KJY
5IWL
5TZ2
5TZT
5TZU
7MYZ
7WN8
7XJF
7YGG
8RP8
1DDF
2NA7
3EWT
3EZQ
3THM
3TJE
Enriched GO Terms of Interacting Partners
?
Response To Mechanical Stimulus
Regulation Of Apoptotic Signaling Pathway
Cellular Response To Stress
Signaling Receptor Activity
Ankyrin-1 Complex
Integrin Binding
Signal Complex Assembly
Regulation Of Apoptotic Process
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Positive Regulation Of Catabolic Process
Cellular Response To Hydrogen Peroxide
Positive Regulation Of Phosphate Metabolic Process
Regulation Of Focal Adhesion Assembly
Regulation Of Toll-like Receptor 3 Signaling Pathway
Regulation Of Programmed Cell Death
Negative Regulation Of Apoptotic Process
Regulation Of Cell-substrate Junction Organization
Regulation Of Proteolysis
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Fibroblast Migration
Positive Regulation Of Metabolic Process
Response To Hyperoxia
Response To Hydrogen Peroxide
Filopodium Membrane
Negative Regulation Of Transport
Transforming Growth Factor Beta Binding
Fibroblast Growth Factor Binding
Negative Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Integrin-mediated Signaling Pathway
Positive Regulation Of Phosphorylation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Positive Regulation Of Macrophage Chemotaxis
Negative Regulation Of Anoikis
Negative Regulation Of Focal Adhesion Assembly
Positive Regulation Of Glycolytic Process
Cellular Response To Reactive Oxygen Species
Cell Motility
Fc Receptor Mediated Stimulatory Signaling Pathway
Cellular Response To Chemical Stress
Multicellular Organismal-level Iron Ion Homeostasis
Symbiont Entry Into Host Cell
Protein Autophosphorylation
Positive Regulation Of Macrophage Migration
Regulation Of Anoikis
Autophagy
Fibronectin Binding
Regulation Of Cell Adhesion
Extracellular Matrix Binding
Regulation Of Cell-matrix Adhesion
Cell Death
Regulation Of Programmed Cell Death
Apoptotic Process
Programmed Cell Death
Regulation Of Apoptotic Process
Apoptotic Signaling Pathway
Death Receptor Binding
Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
Death-inducing Signaling Complex
Regulation Of Protein Metabolic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Cytosol
Regulation Of Cell Communication
Cytoplasm
Regulation Of Signaling
Tumor Necrosis Factor Receptor Binding
Extrinsic Apoptotic Signaling Pathway
Cell Surface Receptor Signaling Pathway
Regulation Of Metabolic Process
Positive Regulation Of Macrophage Differentiation
Signal Transduction
Regulation Of Macromolecule Metabolic Process
Regulation Of Apoptotic Signaling Pathway
Ubiquitin Protein Ligase Binding
Positive Regulation Of Cell Communication
Positive Regulation Of Signal Transduction
Regulation Of Canonical NF-kappaB Signal Transduction
Regulation Of Extrinsic Apoptotic Signaling Pathway
Ripoptosome
CD95 Death-inducing Signaling Complex
Positive Regulation Of Intracellular Signal Transduction
Kinase Binding
Regulation Of Macrophage Differentiation
Regulation Of Primary Metabolic Process
Negative Regulation Of Transporter Activity
Identical Protein Binding
Regulation Of Protein Catabolic Process
Positive Regulation Of Signaling
Response To Mechanical Stimulus
Necroptotic Signaling Pathway
TRAIL-activated Apoptotic Signaling Pathway
Protein Tyrosine Kinase Activity
Regulation Of Multicellular Organismal Process
Regulation Of Immune Response
Positive Regulation Of Protein Metabolic Process
Protein-macromolecule Adaptor Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Phospholipase Activator Activity
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Tagcloud (Difference)
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Tagcloud (Intersection)
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