AKIP1 and MAPK13

Number of citations of the paper that reports this interaction (PubMedID 18624398)
0

Data Source:
BioGRID (two hybrid)

		AKIP1	MAPK13
Description		A-kinase interacting protein 1	mitogen-activated protein kinase 13
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Substrate Adhesion-dependent Cell Spreading Regulation Of Non-canonical NF-kappaB Signal Transduction	MAPK Cascade Response To Osmotic Stress Positive Regulation Of Interleukin-6 Production Cellular Response To Stress Cellular Response To UV Intracellular Signal Transduction Positive Regulation Of Inflammatory Response Stress-activated MAPK Cascade Cellular Response To Hydrogen Peroxide Cellular Response To Interleukin-1 Cellular Response To Sorbitol Cellular Response To Anisomycin Cellular Response To Sodium Arsenite
Pathways			NOD1/2 Signaling Pathway p38MAPK events VEGFA-VEGFR2 Pathway
Drugs			Minocycline KC706 Fostamatinib
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Brain morphology (MOSTest) ( 32665545) Hemoglobin levels ( 32327693)	Birth weight ( 31043758) Blood protein levels ( 30072576) Offspring birth weight ( 31043758)
Interacting Genes		7 interacting genes: BARD1 FHL2 HMGB1 MAPK13 MCPH1 PRKACA SPTAN1	17 interacting genes: AKIP1 ANKLE2 APP ATF2 BTRC EEF2K FGF12 GPX4 HTRA2 MAP2K6 MAP3K4 MAPKAPK3 MAPKAPK5 MAPT MBP SMAD4 SQSTM1
Entrez ID		56672	5603
HPRD ID		12380	09113
Ensembl ID		ENSG00000166452	ENSG00000156711
Uniprot IDs		Q9NQ31	A0A024RD04 O15264
PDB IDs			3COI 4EYJ 4EYM 4MYG 4YNO 5EKN 5EKO 8X23
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nucleobase-containing Compound Metabolic Process Histone H2AK127 Ubiquitin Ligase Activity Regulation Of Protein Export From Nucleus Negative Regulation Of Metabolic Process Histone H2AK129 Ubiquitin Ligase Activity Negative Regulation Of MRNA 3'-end Processing BRCA1-BARD1 Complex Atrial Cardiac Muscle Cell Development Regulation Of Calcium-mediated Signaling Positive Regulation Of Glucose Metabolic Process Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Carbohydrate Catabolic Process Positive Regulation Of Interleukin-6 Production Regulation Of Glucose Metabolic Process Regulation Of Autophagy Positive Regulation Of Myeloid Progenitor Cell Differentiation Negative Regulation Of Apoptotic Cell Clearance Cellular Response To Carbohydrate Stimulus Cellular Response To Sorbitol Specific Granule Lumen Tertiary Granule Lumen Regulation Of Phagocytosis BRCA1-B Complex Regulation Of Nucleocytoplasmic Transport Regulation Of Mismatch Repair C-X-C Chemokine Binding Negative Regulation Of Protein-containing Complex Assembly Alphav-beta3 Integrin-HMGB1 Complex T-helper 1 Cell Activation Positive Regulation Of Mismatch Repair Plasmacytoid Dendritic Cell Activation Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Glycogen Catabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Protein Localization To Lipid Droplet Response To Anisomycin Cellular Response To Anisomycin Response To Sorbitol Flavin-dependent Sulfhydryl Oxidase Activity Regulation Of Intracellular Protein Transport Negative Regulation Of RNA Metabolic Process Nuclear Ubiquitin Ligase Complex BRCA1-C Complex Cellular Response To Radiation Negative Regulation Of Macromolecule Metabolic Process Response To Hormone Negative Regulation Of DNA-templated Transcription Initiation	MAPK Cascade Intracellular Signaling Cassette Intracellular Signal Transduction MAP Kinase Kinase Activity P38MAPK Cascade Regulation Of Protein Metabolic Process Regulation Of Intracellular Signal Transduction Cellular Response To Growth Factor Stimulus Response To Nerve Growth Factor Response To Growth Factor Main Axon Cellular Response To Nerve Growth Factor Stimulus Calcium-dependent Protein Serine/threonine Kinase Activity Brainstem Development Regulation Of Transforming Growth Factor Beta2 Production Cellular Response To Brain-derived Neurotrophic Factor Stimulus Protein Serine/threonine Kinase Activity Calmodulin Binding Protein-containing Complex Adult Locomotory Behavior Developmental Process Regulation Of Cell Communication Signal Transduction Negative Regulation Of Ferroptosis Regulation Of Ferroptosis Protein Kinase Activity Apolipoprotein Binding Identical Protein Binding Astrocyte Activation Apoptotic Process Response To Lead Ion Regulation Of Superoxide Anion Generation Regulation Of Signal Transduction Programmed Cell Death Cell Death Nucleus Positive Regulation Of Superoxide Anion Generation Immune System Process Calcium/calmodulin-dependent Protein Kinase Activity Mitogen-activated Protein Kinase Binding Positive Regulation Of Long-term Synaptic Potentiation Kinase Activity Regulation Of Programmed Cell Death Protein Serine Kinase Activity Amyloid Fibril Formation Regulation Of Superoxide Metabolic Process Protein Phosphatase 2A Binding Immune Response-activating Signaling Pathway Response To Oxidative Stress Central Nervous System Development
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