AKIP1 and MAPK13

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		AKIP1	MAPK13
Gene Name		A kinase (PRKA) interacting protein 1	mitogen-activated protein kinase 13
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Cytosol
	Molecular Function	Protein Binding	Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding
	Biological Process	Substrate Adhesion-dependent Cell Spreading	MAPK Cascade Transcription, DNA-templated Regulation Of Transcription, DNA-templated Response To Stress Response To Osmotic Stress Cell Cycle Ras Protein Signal Transduction Peptidyl-serine Phosphorylation Positive Regulation Of Interleukin-6 Production Intracellular Signal Transduction Vascular Endothelial Growth Factor Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Inflammatory Response
Pathways			Signalling to ERKs Signalling by NGF DSCAM interactions Signaling by VEGF Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways NOD1/2 Signaling Pathway Signalling to RAS p38MAPK events NGF signalling via TRKA from the plasma membrane VEGFA-VEGFR2 Pathway Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: BARD1 MAPK13 PRKACA	15 interactors: AKIP1 ANKLE2 APP ATF2 EEF2K FGF12 GPX4 HTRA2 MAP2K6 MAP3K4 MAPKAPK3 MAPKAPK5 MAPT MBP SMAD4
Entrez ID		56672	5603
HPRD ID		12380	09113
Ensembl ID		ENSG00000166452	ENSG00000156711
Uniprot IDs		Q9NQ31	O15264
PDB IDs			3COI 4EXU 4EYJ 4EYM
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Export From Nucleus Positive Regulation Of Inflammatory Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Peptidyl-serine Phosphorylation Positive Regulation Of Dense Core Granule Biogenesis Cell Cycle Regulation Of Nucleocytoplasmic Transport Negative Regulation Of MRNA 3'-end Processing Histone H3-T6 Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Intracellular Protein Transport Regulation Of Inflammatory Response Peptidyl-serine Autophosphorylation Negative Regulation Of Protein Export From Nucleus Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Regulation Of Protein Catabolic Process Negative Regulation Of Transport Protein K6-linked Ubiquitination Regulation Of Intracellular Transport Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Tight Junction Assembly Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Cell Communication By Electrical Coupling Involved In Cardiac Conduction Response To Parathyroid Hormone Calcium-mediated Signaling Using Intracellular Calcium Source Desmosome Organization Positive Regulation Of Protein Export From Nucleus Cell Communication By Electrical Coupling Cellular Response To Growth Factor Stimulus Activation Of Protein Kinase A Activity Response To Growth Factor Regulation Of Protein Transport Regulation Of Platelet Aggregation Negative Regulation Of Glucose Transport Regulation Of MRNA 3'-end Processing Sperm Capacitation Cellular Response To Epinephrine Stimulus Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Induction Of Positive Chemotaxis Positive Regulation Of Cardiac Muscle Hypertrophy Response To Epinephrine Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Establishment Of Protein Localization Regulation Of Lipopolysaccharide-mediated Signaling Pathway	MAPK Cascade Signal Transduction By Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Regulation Of Cellular Protein Metabolic Process Adult Locomotory Behavior Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Regulation Of Phosphorus Metabolic Process Regulation Of Protein Metabolic Process Activation Of MAPK Activity Regulation Of Protein Phosphorylation Adult Behavior Toll-like Receptor 5 Signaling Pathway Developmental Process Toll-like Receptor 10 Signaling Pathway Phosphorylation Positive Regulation Of Cellular Metabolic Process Intracellular Signal Transduction Response To Stress Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Positive Regulation Of MAP Kinase Activity TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta2 Production MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Protein Modification Process Locomotory Behavior MyD88-dependent Toll-like Receptor Signaling Pathway Phosphate-containing Compound Metabolic Process Toll-like Receptor 4 Signaling Pathway Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Toll-like Receptor Signaling Pathway Response To Organic Substance Cell Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Signaling Positive Regulation Of Signal Transduction Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cell Communication Regulation Of Kinase Activity
Tagcloud ?			alpha3 alpha3beta bap calcification calcifying ccl22 cd14 cd16 cd45 chi3l1 chit1 chitinase diaphyseal distinguished drilled femurs freshly fulfill gpnmb hole implanted ll monocytes monoosteophil monoosteophils osteoactivin osteopontin p38mapkdelta spp1
Tagcloud (Difference) ?			alpha3 alpha3beta bap calcification calcifying ccl22 cd14 cd16 cd45 chi3l1 chit1 chitinase diaphyseal distinguished drilled femurs freshly fulfill gpnmb hole implanted ll monocytes monoosteophil monoosteophils osteoactivin osteopontin p38mapkdelta spp1
Tagcloud (Intersection) ?