CTPS2 and RPL23A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CTPS2	RPL23A
Description		CTP synthase 2	ribosomal protein L23a
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Cytoophidium	Nucleus Nucleolus Cytoplasm Cytosol Ribosome Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding CTP Synthase Activity Protein Binding ATP Binding Ligase Activity Identical Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding Cadherin Binding TORC2 Complex Binding
	Biological Process	Pyrimidine Nucleotide Metabolic Process Pyrimidine Nucleotide Biosynthetic Process CTP Biosynthetic Process Pyrimidine Nucleobase Biosynthetic Process 'de Novo' CTP Biosynthetic Process Small Molecule Metabolic Process	Cytoplasmic Translation Translation
Pathways		Interconversion of nucleotide di- and triphosphates	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs			(S)-3-phenyllactic acid Anisomycin Puromycin Artenimol
Diseases
GWAS		Suicide ( 31476763)	Appendicular lean mass ( 33097823) Total cholesterol levels ( 30275531)
Interacting Genes		6 interacting genes: CTBP2 FGFR1 MTNR1A RPL23A RPL37A SPG21	11 interacting genes: CTPS2 CTTN DUX4 FOXP1 HERC3 IPO5 IPO7 NAP1L1 PTEN TFIP11 TNPO1
Entrez ID		56474	6147
HPRD ID		02305	15998
Ensembl ID		ENSG00000047230	ENSG00000198242
Uniprot IDs		Q9NRF8	P62750
PDB IDs		2V4U 2VKT 3IHL 6PK4 6PK7 7MH1 7MIH 7MII	4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6SXO 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 7QVP 7XNX 7XNY 8A3D 8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G60 8G61 8G6J 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8ONY 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9FPZ 9FQ0 9G8M 9GMO
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Vitamin D3 Metabolic Process Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Positive Regulation Of Mitotic Cell Cycle DNA Replication Receptor-receptor Interaction Ventricular Zone Neuroblast Division Regulation Of Mitotic Cell Cycle DNA Replication Developmental Maturation Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Cementum Mineralization Diphosphate Metabolic Process Fibroblast Growth Factor Receptor Activity Cell Maturation Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-epithelial Signaling Orbitofrontal Cortex Development Negative Regulation Of Fibroblast Growth Factor Production Macromolecule Biosynthetic Process Receptor Complex Positive Regulation Of Phospholipase Activity Forebrain Neuroblast Division Regulation Of Lateral Mesodermal Cell Fate Specification Forebrain Ventricular Zone Progenitor Cell Division Positive Regulation Of Parathyroid Hormone Secretion Melatonin Receptor Activity Ribosome Cytoplasmic Translation Cytosolic Ribosome Cytosolic Large Ribosomal Subunit TORC2 Complex Binding Structural Constituent Of Ribosome Auditory Receptor Cell Development Positive Regulation Of Nuclear Cell Cycle DNA Replication Lung-associated Mesenchyme Development Regulation Of Branching Involved In Salivary Gland Morphogenesis Outer Ear Morphogenesis Positive Regulation Of Lipase Activity Regulation Of Mesodermal Cell Differentiation Mesenchymal-epithelial Cell Signaling Paraxial Mesoderm Development Response To Sodium Phosphate Regulation Of Phosphate Transport CD4 Receptor Binding Salivary Gland Morphogenesis Gene Expression Branching Involved In Salivary Gland Morphogenesis Regulation Of Nuclear Cell Cycle DNA Replication Vitamin D Metabolic Process Inner Ear Receptor Cell Development Ear Development Regulation Of Retinoic Acid Receptor Signaling Pathway	Protein Import Into Nucleus Import Into Nucleus Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding Negative Regulation Of Cell Cycle Dendritic Spine Organization Protein Localization To Nucleus Negative Regulation Of Organ Growth Intracellular Protein Transport Neuron Projection Organization Postsynapse Organization Nuclear Transport Nucleocytoplasmic Transport Small GTPase Binding Negative Regulation Of Synaptic Vesicle Clustering Regulation Of Developmental Growth Cytoplasm Establishment Of Protein Localization To Organelle Nuclear Pore Negative Regulation Of Osteoblast Differentiation Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Spliceosomal Complex Disassembly Positive Regulation Of Interleukin-21 Production CTP Synthase Activity 'de Novo' CTP Biosynthetic Process Positive Regulation Of Protein Localization To Nucleus Negative Regulation Of Developmental Growth Regulation Of Organ Growth Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission U2-type Post-mRNA Release Spliceosomal Complex Cytoophidium Nucleolus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?