CTPS2 and RPL37A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CTPS2	RPL37A
Description		CTP synthase 2	ribosomal protein L37a
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Cytoophidium	Nucleus Cytoplasm Cytosol Ribosome Focal Adhesion Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Synapse Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding CTP Synthase Activity Protein Binding ATP Binding Ligase Activity Identical Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Pyrimidine Nucleotide Metabolic Process Pyrimidine Nucleotide Biosynthetic Process CTP Biosynthetic Process Pyrimidine Nucleobase Biosynthetic Process 'de Novo' CTP Biosynthetic Process Small Molecule Metabolic Process	Cytoplasmic Translation Translation
Pathways		Interconversion of nucleotide di- and triphosphates	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS		Suicide ( 31476763)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) White matter integrity (fractional anisotropy) ( 32358547)
Interacting Genes		6 interacting genes: CTBP2 FGFR1 MTNR1A RPL23A RPL37A SPG21	10 interacting genes: APP BUB3 CTPS2 FBXO7 FOXP1 IFNGR2 LRIF1 MAGEA6 NKX3-1 PRMT1
Entrez ID		56474	6168
HPRD ID		02305	17997
Ensembl ID		ENSG00000047230	ENSG00000197756
Uniprot IDs		Q9NRF8	P61513
PDB IDs		2V4U 2VKT 3IHL 6PK4 6PK7 7MH1 7MIH 7MII	4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 7XNX 7XNY 8A3D 8FKZ 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9G8M 9GMO
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Vitamin D3 Metabolic Process Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Positive Regulation Of Mitotic Cell Cycle DNA Replication Receptor-receptor Interaction Ventricular Zone Neuroblast Division Regulation Of Mitotic Cell Cycle DNA Replication Developmental Maturation Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Cementum Mineralization Diphosphate Metabolic Process Fibroblast Growth Factor Receptor Activity Cell Maturation Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-epithelial Signaling Orbitofrontal Cortex Development Negative Regulation Of Fibroblast Growth Factor Production Macromolecule Biosynthetic Process Receptor Complex Positive Regulation Of Phospholipase Activity Forebrain Neuroblast Division Regulation Of Lateral Mesodermal Cell Fate Specification Forebrain Ventricular Zone Progenitor Cell Division Positive Regulation Of Parathyroid Hormone Secretion Melatonin Receptor Activity Ribosome Cytoplasmic Translation Cytosolic Ribosome Cytosolic Large Ribosomal Subunit TORC2 Complex Binding Structural Constituent Of Ribosome Auditory Receptor Cell Development Positive Regulation Of Nuclear Cell Cycle DNA Replication Lung-associated Mesenchyme Development Regulation Of Branching Involved In Salivary Gland Morphogenesis Outer Ear Morphogenesis Positive Regulation Of Lipase Activity Regulation Of Mesodermal Cell Differentiation Mesenchymal-epithelial Cell Signaling Paraxial Mesoderm Development Response To Sodium Phosphate Regulation Of Phosphate Transport CD4 Receptor Binding Salivary Gland Morphogenesis Gene Expression Branching Involved In Salivary Gland Morphogenesis Regulation Of Nuclear Cell Cycle DNA Replication Vitamin D Metabolic Process Inner Ear Receptor Cell Development Ear Development Regulation Of Retinoic Acid Receptor Signaling Pathway	Macrophage Activation Amyloid-beta Complex Growth Cone Lamellipodium Negative Regulation Of Gene Expression Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Myeloid Leukocyte Activation Regulation Of Mitotic Cell Cycle Leukocyte Activation Microglial Cell Activation Cell Activation Leukocyte Activation Involved In Inflammatory Response GATOR1 Complex Binding Response To Testosterone Positive Regulation Of Androgen Secretion MADS Box Domain Binding Bub1-bub3 Complex Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Myeloid Cell Development Negative Regulation Of Signal Transduction Negative Regulation Of Biosynthetic Process Acetylcholine Receptor Activator Activity PTB Domain Binding Response To Interleukin-1 Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Chemokine Production Negative Regulation Of Transcription By RNA Polymerase II Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Signaling Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Endothelin Production Growth Cone Filopodium Negative Regulation Of Macromolecule Metabolic Process Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Import Nucleus Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Cell Communication Regulation Of Interleukin-1 Beta Production
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