CABP5 and PPP3R1

Number of citations of the paper that reports this interaction (PubMedID 11108966)
0

Data Source:
BioGRID (pull down)

		CABP5	PPP3R1
Description		calcium binding protein 5	protein phosphatase 3 regulatory subunit B, alpha
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Calcineurin Complex Protein Serine/threonine Phosphatase Complex Membrane Sarcolemma Synapse Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Postsynapse Glutamatergic Synapse
	Molecular Function	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Metal Ion Binding	Phosphoprotein Phosphatase Activity Calcium-dependent Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Calmodulin Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Phosphatase Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Signal Transduction	Branching Involved In Blood Vessel Morphogenesis Epithelial To Mesenchymal Transition Protein Import Into Nucleus Heart Development Schwann Cell Development Myelination In Peripheral Nervous System Calcineurin-NFAT Signaling Cascade Protein Localization To Nucleus Positive Regulation Of Transcription By RNA Polymerase II Lung Epithelial Cell Differentiation Positive Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Synaptic Vesicle Cycle Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Postsynaptic Modulation Of Chemical Synaptic Transmission Positive Regulation Of Calcium Ion Import Across Plasma Membrane Negative Regulation Of Calcium Ion Import Across Plasma Membrane
Pathways			Activation of BAD and translocation to mitochondria DARPP-32 events Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization Ca2+ pathway CLEC7A (Dectin-1) induces NFAT activation
Drugs			Myristic acid Voclosporin
Diseases
GWAS		Body mass index ( 31888951) Obesity (extreme) ( 31888951) Refractive error ( 32231278) Urinary metabolite levels in chronic kidney disease ( 31959995)	General cognitive ability ( 29844566) Height ( 25282103) Hip index ( 34021172) Intelligence (MTAG) ( 29326435) Schizophrenia ( 30285260) Urinary potassium excretion ( 31409800)
Interacting Genes		36 interacting genes: ACOT11 ANKRD55 CADPS CEP76 CT55 DDIT4L IKZF3 INCA1 LNX1 LZTS2 MEI4 NME4 PAX4 PPP3R1 PSMA1 REL SDCBP TCF4 TLE5 TNNI1 VPS52 ZBTB42 ZC2HC1C ZKSCAN4 ZNF169 ZNF223 ZNF229 ZNF280A ZNF398 ZNF474 ZNF559 ZNF620 ZNF664 ZNF669 ZNF835 ZNF844	12 interacting genes: CABP1 CABP2 CABP5 CHRNA6 MAP3K5 MYC NAP1L2 NFATC1 NFATC2 PPP3CA PPP3CC RCAN1
Entrez ID		56344	5534
HPRD ID		09537	03195
Ensembl ID		ENSG00000105507	ENSG00000221823
Uniprot IDs		Q9NP86	P63098
PDB IDs			1AUI 1M63 1MF8 2P6B 3LL8 4F0Z 4OR9 4ORA 4ORC 5SVE 6NUC 6NUF 6NUU 7U0T 9B9G 9CHU 9CHV 9CHX
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Metal Ion Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process	Calcineurin-NFAT Signaling Cascade Calcineurin-mediated Signaling Calcium-mediated Signaling Negative Regulation Of Smooth Muscle Cell Differentiation Intracellular Signaling Cassette Myotube Cell Development Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Smooth Muscle Cell Differentiation Calmodulin-dependent Protein Phosphatase Activity Calcium Channel Regulator Activity Negative Regulation Of Calcium Ion Import Across Plasma Membrane Calcineurin Complex Signal Transduction Striated Muscle Cell Development Negative Regulation Of Muscle Cell Differentiation Protein Serine/threonine Phosphatase Complex Positive Regulation Of Kidney Development Positive Regulation Of Calcium Ion Import Across Plasma Membrane Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Muscle Cell Development Regulation Of Calcium-mediated Signaling Regulation Of Cell Differentiation Negative Regulation Of Calcium Ion Import Regulation Of Calcium Ion Import Across Plasma Membrane Positive Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Cell Differentiation Regulation Of Developmental Process Intracellular Signal Transduction Positive Regulation Of Calcium Ion Import Skeletal Muscle Fiber Development Regulation Of Muscle Cell Differentiation Regulation Of Kidney Development Negative Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Developmental Process Regulation Of Calcium Ion Import Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Negative Regulation Of Angiotensin-activated Signaling Pathway Negative Regulation Of Calcium Ion Transport Regulation Of Cell Proliferation Involved In Kidney Morphogenesis Axonemal Basal Plate Positive Regulation Of Calcium-mediated Signaling Calcium Ion Binding Positive Regulation Of Calcium Ion Transmembrane Transport Response To Ischemia Excitatory Postsynaptic Potential Negative Regulation Of Cation Transmembrane Transport
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