KRT24 and KRT2

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRT24	KRT2
Description		keratin 24	keratin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Cornified Envelope Extracellular Space Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization	Keratinocyte Development Epidermis Development Peptide Cross-linking Keratinization Keratinocyte Activation Keratinocyte Proliferation Intermediate Filament Organization Positive Regulation Of Epidermis Development Keratinocyte Migration
Pathways		Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	Keratinization Formation of the cornified envelope
Drugs			Zinc Copper Anthralin Zinc acetate
Diseases			Ichthyosis bullosa of Siemens
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 30929738 31619474 31959851) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		36 interacting genes: AARD ABI2 ABI3 AIRIM AMOT BFSP2 C1orf216 CCDC146 CCHCR1 HGS KRT1 KRT2 KRT20 KRT3 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT78 KRT79 KRT8 KRT80 KRT81 ODAD3 PCM1 PRPH RCOR3 SGF29 SNAPIN TCHP TRIML2 TSGA10IP TXLNA	20 interacting genes: EVPL KRT13 KRT24 KRT25 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 OGT RNF26 SIRPA SMAD3
Entrez ID		192666	3849
HPRD ID		09668	02560
Ensembl ID		ENSG00000167916	ENSG00000172867
Uniprot IDs		Q2M2I5	P35908
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Skin Epidermis Intermediate Filament Keratinization Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Structural Constituent Of Cytoskeleton Cytosol Intermediate Filament Cytoskeleton Extracellular Exosome Actin-based Cell Projection Cytoskeleton Protein Binding Cornified Envelope SCAR Complex Centriole Structural Molecule Activity Peptide Cross-linking Regulation Of Cell Projection Assembly Cell Projection Organization Desmosome	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Keratin Filament Intermediate Filament Structural Molecule Activity Epithelial Cell Differentiation Morphogenesis Of An Epithelium Tissue Morphogenesis Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Cytoskeleton Anatomical Structure Morphogenesis Cellular Developmental Process Cell Differentiation Extracellular Exosome Developmental Process Cytosol Hair Follicle Morphogenesis Epidermis Development Intermediate Filament Cytoskeleton Hair Cycle Process Hair Cycle Tissue Development Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Nitric Oxide Biosynthetic Process Cellular Response To Interleukin-12 Cellular Response To Glucose Stimulus
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