KRT24 and KRT6C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT24	KRT6C
Description		keratin 24	keratin 6C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization	Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 30929738 31619474 31959851) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		36 interacting genes: AARD ABI2 ABI3 AIRIM AMOT BFSP2 C1orf216 CCDC146 CCHCR1 HGS KRT1 KRT2 KRT20 KRT3 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT78 KRT79 KRT8 KRT80 KRT81 ODAD3 PCM1 PRPH RCOR3 SGF29 SNAPIN TCHP TRIML2 TSGA10IP TXLNA	26 interacting genes: ACTN3 GOLGA2 KIFC3 KRT13 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 RNF26 SMARCB1 TFIP11 TRIM54
Entrez ID		192666	286887
HPRD ID		09668	17247
Ensembl ID		ENSG00000167916	ENSG00000170465
Uniprot IDs		Q2M2I5	P48668
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Skin Epidermis Intermediate Filament Keratinization Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Structural Constituent Of Cytoskeleton Cytosol Intermediate Filament Cytoskeleton Extracellular Exosome Actin-based Cell Projection Cytoskeleton Protein Binding Cornified Envelope SCAR Complex Centriole Structural Molecule Activity Peptide Cross-linking Regulation Of Cell Projection Assembly Cell Projection Organization Desmosome	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Epithelial Cell Differentiation Morphogenesis Of An Epithelium Tissue Morphogenesis Supramolecular Fiber Organization Cytoskeleton Organization Cytoskeleton Organelle Organization Anatomical Structure Morphogenesis Cell Differentiation Extracellular Exosome Cellular Developmental Process Developmental Process Hair Cycle Structural Constituent Of Cytoskeleton Epidermis Development Cytosol Hair Follicle Morphogenesis Hair Cycle Process Cell Periphery Tissue Development Z Disc Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Structural Constituent Of Muscle Protein Binding Intermediate Filament Cytoskeleton Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Spliceosomal Complex Disassembly Cornified Envelope
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