BEX1 and MAGEA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BEX1	MAGEA2
Description		brain expressed X-linked 1	MAGE family member A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Regulator Complex Cytoplasm	Nucleus PML Body
	Molecular Function	Transcription Coactivator Binding Signaling Receptor Binding Protein Binding Signaling Adaptor Activity Metal Ion Binding Molecular Function Inhibitor Activity	Protein Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding DNA-binding Transcription Factor Binding
	Biological Process	Signal Transduction Nervous System Development Cell Differentiation Negative Regulation Of Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Protein Catabolic Process Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction By P53 Class Mediator Cellular Senescence Negative Regulation Of Protein Acetylation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		31 interacting genes: AKT1 BAG4 BCAR3 CASP8 CHEK2 CNOT2 CTAG1A CTAG1B CYSRT1 FBXW7 FGFR2 FZR1 GSK3B KLHL20 KRT31 KRT34 MAGEA2 MAGEA2B MDFI MEOX2 NGFR OMP OTP PAX2 PICK1 PIK3CA PTEN PTPN11 SMAD4 TENM1 TEX11	21 interacting genes: ACSM1 ANKRD45 BEX1 BEX2 CCDC185 CEP57 COQ4 COX7C DYNLRB1 MBD3 MDM2 NTAQ1 P4HA3 PHKG2 POLL PSMC1 SEPTIN5 SMARCD1 TNIP3 TP53 TRIM28
Entrez ID		55859	4101
HPRD ID		06460	02165
Ensembl ID		ENSG00000133169	ENSG00000268606
Uniprot IDs		Q9HBH7	P43356
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Developmental Process Developmental Process Ubiquitin Protein Ligase Binding Positive Regulation Of Intracellular Signal Transduction Epithelial Cell Differentiation Regulation Of Intracellular Signal Transduction Cell Differentiation Positive Regulation Of Proteolysis Carbohydrate Homeostasis Positive Regulation Of Catalytic Activity Glucose Homeostasis Regulation Of Protein Ubiquitination Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Protein Ubiquitination PML Body Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Population Proliferation Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Modification Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Post-translational Protein Modification Regulation Of Catalytic Activity Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Programmed Cell Death Identical Protein Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Catabolic Process Negative Regulation Of Macromolecule Metabolic Process ERBB Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Insulin Receptor Signaling Pathway Regulation Of Protein Modification Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process Enzyme-linked Receptor Protein Signaling Pathway Regulation Of RNA Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Intracellular Glucose Homeostasis Negative Regulation Of Protein Acetylation Animal Organ Development	Response To Actinomycin D Cellular Response To Actinomycin D Cellular Response To UV-C Energy Derivation By Oxidation Of Organic Compounds Cellular Response To Antibiotic Response To UV-C Protein-containing Complex SUMO Transferase Activity
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