MAGEA2 and CCDC185

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEA2	CCDC185
Description		MAGE family member A2	coiled-coil domain containing 185
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus PML Body
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding DNA-binding Transcription Factor Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Catabolic Process Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction By P53 Class Mediator Cellular Senescence Negative Regulation Of Protein Acetylation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		21 interacting genes: ACSM1 ANKRD45 BEX1 BEX2 CCDC185 CEP57 COQ4 COX7C DYNLRB1 MBD3 MDM2 NTAQ1 P4HA3 PHKG2 POLL PSMC1 SEPTIN5 SMARCD1 TNIP3 TP53 TRIM28	49 interacting genes: AMOTL2 BACH2 CADPS CALCOCO2 CBY2 CCDC136 CCDC85B CDR2L CEP44 CEP57 EVI5 EVI5L FAM161A GEMIN4 GOLGA2 GOLGA6L9 GRIPAP1 HSF2BP IKZF1 ISY1-RAB43 KRT15 KRT27 KRT35 KRT40 KRTAP10-7 KRTAP4-12 KXD1 LURAP1 MAGEA11 MAGEA2 MAGEA2B MAGEA6 MCC MDFI MID2 MKRN3 MTUS2 NAP1L2 NUTM1 PDLIM7 PKNOX2 PPP1R12C SPRED1 SPTA1 TBC1D1 TRAF1 TRIM27 VPS52 ZRANB1
Entrez ID		4101	164127
HPRD ID		02165	08761
Ensembl ID		ENSG00000268606	ENSG00000178395
Uniprot IDs		P43356	Q8N715
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Actinomycin D Cellular Response To Actinomycin D Cellular Response To UV-C Energy Derivation By Oxidation Of Organic Compounds Cellular Response To Antibiotic Response To UV-C Protein-containing Complex SUMO Transferase Activity	Keratin Filament Cytoskeleton Intermediate Filament Structural Constituent Of Skin Epidermis Negative Regulation Of Protein Acetylation Intermediate Filament Organization Microtubule Binding Protein Binding Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytosol PML Body Negative Regulation Of Protein Sumoylation Histone Deacetylase Binding Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Viral Transcription Identical Protein Binding Suppression Of Viral Release By Host
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