BEX1 and TENM1

Number of citations of the paper that reports this interaction (PubMedID 25648896)
70

Data Source:
BioGRID (two hybrid)

		BEX1	TENM1
Description		brain expressed X-linked 1	teneurin transmembrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Regulator Complex Cytoplasm	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytoskeleton Plasma Membrane Membrane Nuclear Matrix Nuclear Speck Neuron Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Coactivator Binding Signaling Receptor Binding Protein Binding Signaling Adaptor Activity Metal Ion Binding Molecular Function Inhibitor Activity	Heparin Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Signal Transduction Nervous System Development Cell Differentiation Negative Regulation Of Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase III Immune Response Signal Transduction Neuropeptide Signaling Pathway Nervous System Development Negative Regulation Of Cell Population Proliferation Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of MAP Kinase Activity Neuron Development Positive Regulation Of Filopodium Assembly Positive Regulation Of Intracellular Protein Transport
Pathways
Drugs
Diseases
GWAS
Interacting Genes		31 interacting genes: AKT1 BAG4 BCAR3 CASP8 CHEK2 CNOT2 CTAG1A CTAG1B CYSRT1 FBXW7 FGFR2 FZR1 GSK3B KLHL20 KRT31 KRT34 MAGEA2 MAGEA2B MDFI MEOX2 NGFR OMP OTP PAX2 PICK1 PIK3CA PTEN PTPN11 SMAD4 TENM1 TEX11	12 interacting genes: APBB1 BEX1 CSNK2B FIBP MACF1 MBD1 NUBP1 PICALM POLR2J PTPN12 RACK1 SORBS1
Entrez ID		55859	10178
HPRD ID		06460	06669
Ensembl ID		ENSG00000133169	ENSG00000009694
Uniprot IDs		Q9HBH7	B7ZMH4 Q9UKZ4
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Developmental Process Developmental Process Ubiquitin Protein Ligase Binding Positive Regulation Of Intracellular Signal Transduction Epithelial Cell Differentiation Regulation Of Intracellular Signal Transduction Cell Differentiation Positive Regulation Of Proteolysis Carbohydrate Homeostasis Positive Regulation Of Catalytic Activity Glucose Homeostasis Regulation Of Protein Ubiquitination Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Protein Ubiquitination PML Body Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Population Proliferation Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Modification Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Post-translational Protein Modification Regulation Of Catalytic Activity Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Programmed Cell Death Identical Protein Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Catabolic Process Negative Regulation Of Macromolecule Metabolic Process ERBB Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Insulin Receptor Signaling Pathway Regulation Of Protein Modification Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process Enzyme-linked Receptor Protein Signaling Pathway Regulation Of RNA Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Intracellular Glucose Homeostasis Negative Regulation Of Protein Acetylation Animal Organ Development	Low-density Lipoprotein Particle Receptor Binding Nucleus Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Membrane
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