MAGEA2 and ANKRD45

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEA2	ANKRD45
Description		MAGE family member A2	ankyrin repeat domain 45
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus PML Body	Cytoplasm Centrosome Cytosol Plasma Membrane Midbody Cleavage Furrow Flemming Body
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding DNA-binding Transcription Factor Binding	Molecular_function Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Catabolic Process Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction By P53 Class Mediator Cellular Senescence Negative Regulation Of Protein Acetylation	Cell Population Proliferation
Pathways
Drugs
Diseases
GWAS			Feeling tense ( 29500382) General cognitive ability ( 29844566) Mosquito bite size ( 28199695) Neurociticism ( 29500382)
Interacting Genes		21 interacting genes: ACSM1 ANKRD45 BEX1 BEX2 CCDC185 CEP57 COQ4 COX7C DYNLRB1 MBD3 MDM2 NTAQ1 P4HA3 PHKG2 POLL PSMC1 SEPTIN5 SMARCD1 TNIP3 TP53 TRIM28	5 interacting genes: APP LHX3 MAGEA2 MAGEA2B TRIM54
Entrez ID		4101	339416
HPRD ID		02165	13501
Ensembl ID		ENSG00000268606	ENSG00000183831
Uniprot IDs		P43356	Q5TZF3
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Actinomycin D Cellular Response To Actinomycin D Cellular Response To UV-C Energy Derivation By Oxidation Of Organic Compounds Cellular Response To Antibiotic Response To UV-C Protein-containing Complex SUMO Transferase Activity	Negative Regulation Of Protein Acetylation Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Sumoylation Regulation Of Ubiquitin-protein Transferase Activity Cellular Senescence Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Post-translational Protein Modification Signal Transduction By P53 Class Mediator Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Ubiquitination Histone Deacetylase Binding PML Body Medial Motor Column Neuron Differentiation Prolactin Secreting Cell Differentiation PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Metabolic Process Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling DNA-binding Transcription Factor Binding Ventral Spinal Cord Interneuron Specification Somatotropin Secreting Cell Differentiation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Protein Ubiquitination Regulation Of Spontaneous Synaptic Transmission Negative Regulation Of Transcription By RNA Polymerase II NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity
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