PECR and PEX5

Number of citations of the paper that reports this interaction (PMID 22002062)
8

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		PECR	PEX5
Gene Name		peroxisomal trans-2-enoyl-CoA reductase	peroxisomal biogenesis factor 5
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Membrane Intracellular Membrane-bounded Organelle	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex
	Molecular Function	Receptor Binding 2,4-dienoyl-CoA Reductase (NADPH) Activity Trans-2-enoyl-CoA Reductase (NADPH) Activity	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Fatty Acid Biosynthetic Process Phytol Metabolic Process Oxidation-reduction Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization
Pathways
Drugs
Diseases
GWAS		Alcohol dependence ( 19581569)	IgG glycosylation ( 23382691)
Protein-Protein Interactions		2 interactors: ISL1 PEX5	68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772
Entrez ID		55825	5830
HPRD ID		09320	02684
Ensembl ID		ENSG00000115425	ENSG00000139197
Uniprot IDs		Q9BY49	B4DR50 B4E0T2 P50542
PDB IDs		1YXM	1FCH 2C0L 2C0M 2J9Q 2W84 3R9A
Enriched GO Terms of Interacting Partners?		Central Nervous System Neuron Differentiation Positive Regulation Of Granulocyte Colony-stimulating Factor Production Positive Regulation Of Macrophage Colony-stimulating Factor Production Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Regulation Of Macrophage Colony-stimulating Factor Production Peripheral Nervous System Neuron Axonogenesis Visceral Motor Neuron Differentiation Protein Import Into Peroxisome Matrix, Docking Sensory System Development Negative Regulation Of Protein Homodimerization Activity Cardiac Cell Fate Determination Forebrain Development Positive Regulation Of Interleukin-1 Alpha Production Negative Regulation Of Protein Homooligomerization Protein Import Into Peroxisome Membrane Protein To Membrane Docking Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Peroxisomal Membrane Transport Negative Regulation Of Protein Oligomerization Trigeminal Nerve Development Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Peripheral Nervous System Neuron Development Regulation Of Secondary Heart Field Cardioblast Proliferation Brain Development Cardiac Muscle Cell Myoblast Differentiation Protein Import Into Peroxisome Matrix Head Development Cell Migration Outflow Tract Septum Morphogenesis Cardioblast Differentiation Secondary Heart Field Specification Spinal Cord Motor Neuron Cell Fate Specification Cell Motility Atrial Septum Morphogenesis Regulation Of Protein Homodimerization Activity Cardiac Right Ventricle Morphogenesis Heart Formation Central Nervous System Development Atrial Septum Development Retinal Ganglion Cell Axon Guidance Pharyngeal System Development Endocardial Cushion Morphogenesis Regulation Of Intracellular Estrogen Receptor Signaling Pathway Specification Of Organ Identity Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Very Long-chain Fatty Acid Metabolic Process Neuron Differentiation	Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process
Tagcloud ?			behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?			behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?