ASF1B and AKAP8L

		ASF1B	AKAP8L
Description		anti-silencing function 1B histone chaperone	A-kinase anchoring protein 8 like
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	Protein Binding Histone Binding Histone Chaperone Activity	DNA Binding RNA Binding Protein Binding Lamin Binding Zinc Ion Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding
	Biological Process	Blastocyst Hatching Chromatin Organization Nucleosome Assembly DNA Replication-dependent Chromatin Assembly Spermatogenesis Cell Differentiation	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly
Pathways			Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS			Red blood cell count ( 32888494)
Interacting Genes		13 interacting genes: ASF1A CDIN1 CHAF1A CHAF1B H3-3A H3C3 H3C6 H4C16 H4C6 HCFC1 TAF1 TLK1 TLK2	60 interacting genes: ABI2 ATOSB ATPAF2 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 DSCR9 EMD ENKD1 FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 HUNK INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PRKAA2 PRKACA PRPF40A PTP4A2 RAMAC RTP5 RUSC1 SAMD4A SAXO1 SAXO4 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366
Entrez ID		55723	26993
HPRD ID		16460	10641
Ensembl ID		ENSG00000105011	ENSG00000011243
Uniprot IDs		Q9NVP2	Q9ULX6
PDB IDs		5BNX 5BO0 7V1M 7VCQ
Enriched GO Terms of Interacting Partners?		Nucleosome Assembly Protein-DNA Complex Assembly Chromatin Organization Nucleosome Organization Chromatin Remodeling Protein-containing Complex Structural Constituent Of Chromatin DNA Replication-dependent Chromatin Assembly Nucleosome Telomere Organization Protein-containing Complex Assembly Chromosome Organization Protein Heterodimerization Activity Protein-containing Complex Organization Nucleus Nucleoplasm CAF-1 Complex Chromosome Protein Localization To Chromatin Cellular Component Assembly DNA Damage Response Protein Localization To Chromosome CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Chromatin RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Chromatin Organization MLL1 Complex Chromosome, Telomeric Region Regulation Of Megakaryocyte Differentiation Protein Localization To Chromosome, Centromeric Region Chromatin Binding DNA Binding Positive Regulation Of Androgen Receptor Signaling Pathway Cellular Response To Stress Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Epigenetic Regulation Of Gene Expression Negative Regulation Of Protein Autoubiquitination Cadherin Binding Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Phosphorylation Protein Serine Kinase Activity Negative Regulation Of Myeloid Cell Differentiation Negative Regulation Of Chromosome Condensation Acetyl-CoA Binding Phosphorylation Muscle Cell Differentiation Pericentric Heterochromatin Formation Release From Viral Latency	Protein Binding Sperm Flagellum
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