KIF27 and MAGEA6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KIF27	MAGEA6
Description		kinesin family member 27	MAGE family member A6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytoskeleton Kinesin Complex Microtubule Cilium Cell Projection	Nucleus
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity	Protein Binding Histone Deacetylase Binding
	Biological Process	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Microtubule-based Movement Ventricular System Development Cell Projection Organization Establishment Of Localization In Cell Cilium Assembly	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Multiple sclerosis ( 31604244) Reaction time ( 29844566) Waist circumference adjusted for body mass index ( 34021172)	Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		3 interacting genes: FOXP1 MAGEA3 MAGEA6	75 interacting genes: ACOT7 ACTN3 AKAP9 ANKRD26P1 APOA4 ARFIP1 ATOSA ATP6V1G1 ATPAF2 BCL7B BET1 BFSP2 BOLA3 C1orf216 CAMTA2 CBFA2T2 CCDC146 CCDC185 CCDC187 CCDC24 COL4A6 CTF1 DLGAP3 DLGAP4 DNTTIP1 ELMOD3 EXOC5 FRMPD1 GADD45GIP1 GCSH GFOD1 HAUS1 HLA-DRB4 HNRNPM IQUB KIF27 KLHL38 LCORL LIN37 LIN52 LSM2 MCM7 MCRS1 MED21 MID2 MIPOL1 MORN3 MSGN1 NCK2 NOSTRIN PCBD2 PDE4D PRKAA1 RASSF10 RASSF4 RCOR3 REX1BD RPL37A RUSC1 S100A14 S100A9 SH2D4A SMARCD1 SNAP47 SNX4 SON STAMBPL1 STX5 TRIM26 TRIM28 TSPYL6 TULP3 TXNDC9 XRCC4 ZNF76
Entrez ID		55582	4105
HPRD ID		11179	02168
Ensembl ID		ENSG00000165115	ENSG00000197172
Uniprot IDs		Q86VH2	P43360
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Autophagy Histone Deacetylase Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Interleukin-21 Production Negative Regulation Of Programmed Cell Death Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Regulation Of RNA Metabolic Process Osteoclast Development Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Endothelial Tube Morphogenesis Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cell Communication Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Negative Regulation Of Signaling Monocyte Activation Endothelial Cell Activation T Follicular Helper Cell Differentiation Caspase Binding Regulation Of Autophagy Negative Regulation Of Catabolic Process Beta-catenin-TCF Complex Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of B Cell Apoptotic Process Striatum Development Regulation Of Defense Response To Bacterium Negative Regulation Of Androgen Receptor Signaling Pathway Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Regulation Of Monocyte Differentiation Core Promoter Sequence-specific DNA Binding Negative Regulation Of Anoikis Regulation Of B Cell Apoptotic Process Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Protein Processing Regulation Of Intracellular Signal Transduction	Protein Binding SNARE Complex Suppression Of Viral Release By Host
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