CDC42BPG and RHOQ

Number of citations of the paper that reports this interaction (PMID 15194684)
3

Data Source:
BioGRID (pull down)

		CDC42BPG	RHOQ
Gene Name		CDC42 binding protein kinase gamma (DMPK-like)	ras homolog family member Q
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cell Leading Edge	Cytosol Actin Filament Plasma Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Small GTPase Regulator Activity Protein Binding ATP Binding	GTPase Activity Profilin Binding GTP Binding GBD Domain Binding
	Biological Process	Protein Phosphorylation Actin Cytoskeleton Reorganization Intracellular Signal Transduction Regulation Of Catalytic Activity	Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Glucose Import Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Filopodium Assembly Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Pathways			Rho GTPase cycle Signaling by Rho GTPases Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS		Urate levels ( 21768215)
Protein-Protein Interactions		4 interactors: CDC42 RAC1 RHOQ TBK1	18 interactors: CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL
Entrez ID		55561	23433
HPRD ID		13013	05791
Ensembl ID		ENSG00000171219
Uniprot IDs		Q6DT37	P17081
PDB IDs			2ATX
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Projection Assembly Positive Regulation Of Cell Projection Organization Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Cellular Component Biogenesis Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Filopodium Assembly Regulation Of Phosphatidylinositol 3-kinase Activity Immune Response-regulating Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Regulation Of Lipid Kinase Activity Regulation Of Cytoskeleton Organization Intracellular Signal Transduction Positive Regulation Of DNA Replication T Cell Costimulation Positive Regulation Of Peptidyl-serine Phosphorylation Actin Cytoskeleton Organization Small GTPase Mediated Signal Transduction Positive Regulation Of Immune Response Actin Filament-based Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Phosphorylation Regulation Of Peptidyl-serine Phosphorylation Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cell-substrate Adhesion Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of DNA Replication Positive Regulation Of Phosphorylation Regulation Of Immune Response Regulation Of Signal Transduction Epidermal Cell Differentiation Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Positive Regulation Of DNA Metabolic Process Regulation Of Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Signaling Embryonic Olfactory Bulb Interneuron Precursor Migration	Positive Regulation Of Cell Projection Organization Positive Regulation Of Pseudopodium Assembly Regulation Of Cell Projection Assembly Regulation Of Cell Projection Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Positive Regulation Of Cellular Component Biogenesis Golgi Vesicle Budding Positive Regulation Of Protein Complex Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Membrane Budding Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Regulation Of Cytoskeleton Organization Regulation Of Catalytic Activity Intracellular Signal Transduction Regulation Of Cellular Component Size Actin Cytoskeleton Organization Regulation Of Cellular Component Organization Regulation Of Protein Complex Assembly Small GTPase Mediated Signal Transduction Localization Within Membrane Vesicle-mediated Transport Actin Filament-based Process Positive Regulation Of Hydrolase Activity Regulation Of Cell Shape Tight Junction Assembly Rho Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Ras GTPase Activity Cell Junction Assembly Regulation Of GTPase Activity Vesicle Organization Cell-cell Junction Organization Ras Protein Signal Transduction Apical Junction Assembly Organelle Organization Positive Regulation Of Rho GTPase Activity COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Regulation Of Organelle Organization Regulation Of Ras GTPase Activity Golgi Vesicle Transport Regulation Of Rho GTPase Activity Positive Regulation Of Catalytic Activity
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