CDC42BPG

Description		CDC42 binding protein kinase gamma
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Cell Leading Edge Centriolar Satellite
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Actin Cytoskeleton Organization Actomyosin Structure Organization
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Gout (combined type) ( 32238385) Serum metabolite levels ( 33031748) Serum uric acid levels ( 29124443) Urate levels ( 21768215)
Interacting Genes		4 interacting genes: CDC42 RAC1 RHOQ TBK1
Entrez ID		55561
HPRD ID		13013
Ensembl ID		ENSG00000171219
Uniprot IDs		Q6DT37
PDB IDs
Enriched GO Terms of Interacting Partners?		GBD Domain Binding G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Thioesterase Binding Establishment Or Maintenance Of Cell Polarity Regulation Of Cell Projection Assembly GTP-dependent Protein Binding Intracellular Signaling Cassette Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Lamellipodium Assembly Actin Filament Organization Small GTPase-mediated Signal Transduction Positive Regulation Of Filopodium Assembly Phagocytosis, Engulfment Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Lamellipodium Organization GTPase Activity Regulation Of Actin Cytoskeleton Organization GTP Binding Regulation Of Lamellipodium Assembly Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Actin Cytoskeleton Organization Positive Regulation Of Cell Projection Organization Regulation Of Actin Filament-based Process Regulation Of Filopodium Assembly Membrane Invagination Cortical Cytoskeleton Organization Actin Filament-based Process Regulation Of Lamellipodium Organization Non-canonical Wnt Signaling Pathway Positive Regulation Of Stress Fiber Assembly Endocytosis Protein Kinase Binding Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Actin Filament Bundle Assembly Supramolecular Fiber Organization Nucleotide Binding G Protein Activity Positive Regulation Of Cellular Component Biogenesis Regulation Of Cytoskeleton Organization Intracellular Signal Transduction Cytoplasmic Ribonucleoprotein Granule Actin Filament Establishment Of Cell Polarity Import Into Cell Cell Surface Receptor Signaling Pathway Regulation Of Stress Fiber Assembly Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization
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