PPP6C and TIPRL

Number of citations of the paper that reports this interaction (PMID 16085932)
43

Data Source:
BioGRID (pull down, affinity chromatography technology)

		PPP6C	TIPRL
Gene Name		protein phosphatase 6, catalytic subunit	TOR signaling pathway regulator
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Dephosphorylation	DNA Damage Checkpoint Negative Regulation Of Protein Phosphatase Type 2A Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: IGBP1 NFKBIE PRKDC TGFBR1 TIPRL	4 interactors: APP PPP2CB PPP4C PPP6C
Entrez ID		5537	261726
HPRD ID		02141	14608
Ensembl ID		ENSG00000119414	ENSG00000143155
Uniprot IDs		O00743	O75663
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Phosphorus Metabolic Process Negative Regulation Of Dephosphorylation Cell Activation Peptidyl-serine Phosphorylation Regulation Of Dephosphorylation Negative Regulation Of Protein Phosphatase Type 2A Activity D-serine Transport DNA Damage Checkpoint B Cell Activation Regulation Of Protein Import Into Nucleus Regulation Of Protein Phosphatase Type 2A Activity Apoptotic Process Regulation Of Protein Localization To Nucleus Programmed Cell Death Regulation Of Nucleocytoplasmic Transport Cell Cycle Process Cell Death Death Cell Cycle Checkpoint Pro-B Cell Differentiation Anterior/posterior Pattern Specification Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Protein Dephosphorylation Regulation Of Intracellular Protein Transport Cell Fate Commitment Regulation Of Phosphorylation Positive Regulation Of Transcription, DNA-templated Cell Cycle Immunoglobulin V(D)J Recombination Parathyroid Gland Development Negative Regulation Of Phosphoprotein Phosphatase Activity T Cell Receptor V(D)J Recombination B Cell Lineage Commitment Regulation Of Apoptotic Process Lymphoid Progenitor Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Endothelial Cell Activation Positive Regulation Of Gene Expression Regulation Of Cell Death Negative Regulation Of Phosphorylation Negative Regulation Of Hydrolase Activity Positive Regulation Of Cellular Biosynthetic Process Ectopic Germ Cell Programmed Cell Death Pathway-restricted SMAD Protein Phosphorylation Lymphocyte Activation Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of Microtubule-based Movement Regulation Of Intracellular Transport Negative Regulation Of Cell Cycle Regulation Of SMAD Protein Import Into Nucleus	Dephosphorylation Phosphate-containing Compound Metabolic Process Synaptic Growth At Neuromuscular Junction Cellular Protein Modification Process Collateral Sprouting In Absence Of Injury Protein Dephosphorylation Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Cellular Protein Metabolic Process Neuron Remodeling Response To Oxidative Stress Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Metabolic Process Cellular Copper Ion Homeostasis
Tagcloud ?		actionable adamts18 col1a1 d816 dgki epha4 epha7 g12 g13 gna11 gnaq gucy2c k642 kalrn l576 melanomas mined ngs nras pik3r4 prkaa2 q209 q61 stk31 taf1l trpm6 v559 v600 w557
Tagcloud (Difference) ?		actionable adamts18 col1a1 d816 dgki epha4 epha7 g12 g13 gna11 gnaq gucy2c k642 kalrn l576 melanomas mined ngs nras pik3r4 prkaa2 q209 q61 stk31 taf1l trpm6 v559 v600 w557
Tagcloud (Intersection) ?