PPP6C and IGBP1

Number of citations of the paper that reports this interaction (PMID 9647778)
44

Data Source:
HPRD (two hybrid)

		PPP6C	IGBP1
Gene Name		protein phosphatase 6, catalytic subunit	immunoglobulin (CD79A) binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Cytoplasm Microtubule
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding	Protein Binding Protein Phosphatase Type 2A Regulator Activity Protein Domain Specific Binding Mitogen-activated Protein Kinase Kinase Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Dephosphorylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Negative Regulation Of Stress-activated MAPK Cascade Response To Tumor Necrosis Factor Positive Regulation Of Dephosphorylation Negative Regulation Of Protein Dephosphorylation B Cell Activation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Microtubule-based Movement Response To Interleukin-1 Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: IGBP1 NFKBIE PRKDC TGFBR1 TIPRL	9 interactors: APP LINC01257 LOC81691 MID1 MID2 PPP2CA PPP4C PPP6C S100A13
Entrez ID		5537	3476
HPRD ID		02141	02140
Ensembl ID		ENSG00000119414	ENSG00000089289
Uniprot IDs		O00743	P78318
PDB IDs			4IYP
Enriched GO Terms of Interacting Partners?		Regulation Of Phosphorus Metabolic Process Negative Regulation Of Dephosphorylation Cell Activation Peptidyl-serine Phosphorylation Regulation Of Dephosphorylation Negative Regulation Of Protein Phosphatase Type 2A Activity D-serine Transport DNA Damage Checkpoint B Cell Activation Regulation Of Protein Import Into Nucleus Regulation Of Protein Phosphatase Type 2A Activity Apoptotic Process Regulation Of Protein Localization To Nucleus Programmed Cell Death Regulation Of Nucleocytoplasmic Transport Cell Cycle Process Cell Death Death Cell Cycle Checkpoint Pro-B Cell Differentiation Anterior/posterior Pattern Specification Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Protein Dephosphorylation Regulation Of Intracellular Protein Transport Cell Fate Commitment Regulation Of Phosphorylation Positive Regulation Of Transcription, DNA-templated Cell Cycle Immunoglobulin V(D)J Recombination Parathyroid Gland Development Negative Regulation Of Phosphoprotein Phosphatase Activity T Cell Receptor V(D)J Recombination B Cell Lineage Commitment Regulation Of Apoptotic Process Lymphoid Progenitor Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Endothelial Cell Activation Positive Regulation Of Gene Expression Regulation Of Cell Death Negative Regulation Of Phosphorylation Negative Regulation Of Hydrolase Activity Positive Regulation Of Cellular Biosynthetic Process Ectopic Germ Cell Programmed Cell Death Pathway-restricted SMAD Protein Phosphorylation Lymphocyte Activation Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of Microtubule-based Movement Regulation Of Intracellular Transport Negative Regulation Of Cell Cycle Regulation Of SMAD Protein Import Into Nucleus	Protein Localization To Microtubule Protein Localization To Cytoskeleton Interleukin-1 Alpha Secretion Dephosphorylation Immune Response Synaptic Growth At Neuromuscular Junction Regulation Of Receptor Activity Regulation Of Signal Transduction Depurination Collateral Sprouting In Absence Of Injury Phosphate-containing Compound Metabolic Process Regulation Of Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Intracellular Signal Transduction Cellular Protein Modification Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Interleukin-1 Secretion Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of Peptidyl-tyrosine Phosphorylation Axon Choice Point Recognition DNA Dealkylation Involved In DNA Repair Base-excision Repair, AP Site Formation Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Dephosphorylation Neuron Remodeling Mitotic Nuclear Envelope Reassembly Immune System Process Protein Heterotrimerization Nuclear Envelope Reassembly Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Cell Development Cellular Localization Exocytosis Negative Regulation Of Viral Entry Into Host Cell Deoxyribose Phosphate Catabolic Process Cellular Copper Ion Homeostasis Positive Regulation Of Signal Transduction Negative Regulation Of Epithelial To Mesenchymal Transition Cellular Protein Metabolic Process Regulation Of Viral Entry Into Host Cell Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Viral Transcription Regulation Of Phosphorylation Regulation Of Viral Release From Host Cell Negative Regulation Of JAK-STAT Cascade
Tagcloud ?		actionable adamts18 col1a1 d816 dgki epha4 epha7 g12 g13 gna11 gnaq gucy2c k642 kalrn l576 melanomas mined ngs nras pik3r4 prkaa2 q209 q61 stk31 taf1l trpm6 v559 v600 w557
Tagcloud (Difference) ?		actionable adamts18 col1a1 d816 dgki epha4 epha7 g12 g13 gna11 gnaq gucy2c k642 kalrn l576 melanomas mined ngs nras pik3r4 prkaa2 q209 q61 stk31 taf1l trpm6 v559 v600 w557
Tagcloud (Intersection) ?