TMEM176A and RIDA

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		TMEM176A	RIDA
Description		transmembrane protein 176A	reactive intermediate imine deaminase A
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Peroxisome Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding Hydrolase Activity RNA Endonuclease Activity Producing 3'-phosphomonoesters, Hydrolytic Mechanism Deaminase Activity 2-iminobutanoate/2-iminopropanoate Deaminase 2-iminobutanoate Deaminase Activity 2-iminopropanoate Deaminase Activity
	Biological Process	Negative Regulation Of Dendritic Cell Differentiation	MRNA Catabolic Process Lipid Metabolic Process Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Translation L-threonine Catabolic Process To Glycine MRNA Destabilization Regulation Of Primary Metabolic Process
Pathways			Threonine catabolism
Drugs
Diseases
GWAS		Forced expiratory volume in 1 second (occupational environmental exposures interaction) ( 25979521) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Height ( 20881960 23563607) Metabolite levels ( 23823483) Serum alkaline phosphatase levels ( 33547301) Serum metabolite concentrations in chronic kidney disease ( 29545352) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		16 interacting genes: CD79A CERS4 GOLM1 HIVEP1 KCNK5 MTIF3 RETREG3 RIDA SCD5 SGPL1 SLC71A2 TGM2 TIMMDC1 TMEM176B TMX2 VKORC1	10 interacting genes: BANP DEAF1 HIVEP1 HPD MDM2 MT-CO2 SERPINA5 SPEN TMEM176A TRIB3
Entrez ID		55365	10247
HPRD ID		13635	03924
Ensembl ID		ENSG00000002933	ENSG00000132541
Uniprot IDs		A0A090N8H6 Q96HP8	P52758
PDB IDs			1ONI
Enriched GO Terms of Interacting Partners?		Membrane Peptide Dopaminyltransferase Activity Endoplasmic Reticulum Histone Serotonyltransferase Activity Peptide Histaminyltransferase Activity Protein-glutamine Glutaminase Activity Peptide Noradrenalinyltransferase Activity Peptide Serotonyltransferase Activity Histone Dopaminyltransferase Activity Endoplasmic Reticulum Membrane Sphinganine-1-phosphate Aldolase Activity 2-iminopropanoate Deaminase Activity 2-iminobutanoate/2-iminopropanoate Deaminase L-threonine Catabolic Process To Glycine RNA Endonuclease Activity Producing 3'-phosphomonoesters, Hydrolytic Mechanism 2-iminobutanoate Deaminase Activity Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Protein Deamination L-threonine Catabolic Process Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Palmitoyl-CoA 9-desaturase Activity Acyl-CoA Desaturase Activity Mitochondrial Translational Initiation Bone Development IgM B Cell Receptor Complex Cellular Response To Serotonin Threonine Metabolic Process N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase Activity Stearoyl-CoA 9-desaturase Activity	Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Transcription Repressor Complex Response To Formaldehyde Cellular Response To Vitamin B1 Protein C Inhibitor-coagulation Factor V Complex Protein C Inhibitor-TMPRSS7 Complex Protein C Inhibitor-PLAU Complex Protein C Inhibitor-TMPRSS11E Complex Protein C Inhibitor-coagulation Factor Xa Complex Protein C Inhibitor-KLK3 Complex Protein C Inhibitor-plasma Kallikrein Complex Protein C Inhibitor-thrombin Complex Protein C Inhibitor-coagulation Factor XI Complex Protein C Inhibitor-PLAT Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Body 4-hydroxyphenylpyruvate Dioxygenase Activity Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Seminal Clot Liquefaction Response To Vitamin B1 Response To Water-immersion Restraint Stress Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Cellular Response To Actinomycin D Platelet Dense Tubular Network Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen NEDD8 Ligase Activity Response To Actinomycin D Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Positive Regulation Of Proteasomal Protein Catabolic Process Acrosin Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Cellular Response To UV-C Ubiquitin-protein Transferase Regulator Activity
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