RNF14 and NCOA4

Number of citations of the paper that reports this interaction (PMID 10085091)
38

Data Source:
HPRD (in vivo, in vitro)

		RNF14	NCOA4
Gene Name		ring finger protein 14	nuclear receptor coactivator 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Androgen Receptor Binding	Transcription Coactivator Activity Androgen Receptor Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Protein Ubiquitination Androgen Receptor Signaling Pathway Response To Estradiol Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway	Transcription, DNA-templated Male Gonad Development Response To Hormone Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978)
Protein-Protein Interactions		22 interactors: AR DACH1 ESR1 FAM46A HNF1A HNRNPA1 NCOA4 NR3C1 PHF7 TAGLN TNFAIP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2U UBE2V1 UBE2W VDR	11 interactors: AKT1 AR ATXN2 ESR1 GTF2B KAT2B NR3C1 PPARG RNF14 RXRA VDR
Entrez ID		9604	8031
HPRD ID		05745	03584
Ensembl ID		ENSG00000013561	ENSG00000138293
Uniprot IDs		B7Z229 Q9UBS8	B2R5V0 B4DF87 B4DZ85 Q13772 Q96E88
PDB IDs			1T5Z
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Protein K63-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Intracellular Steroid Hormone Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Steroid Hormone Mediated Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Innate Immune Response Response To Organic Substance Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Hormone-mediated Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Protein Monoubiquitination Cellular Protein Catabolic Process Mammary Gland Branching Involved In Pregnancy Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Protein Catabolic Process Cellular Response To Organic Substance Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress ISG15-protein Conjugation Regulation Of DNA-templated Transcription In Response To Stress Mammary Gland Duct Morphogenesis Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Lipid TRIF-dependent Toll-like Receptor Signaling Pathway Cellular Protein Modification Process Cellular Response To Stress Developmental Process Involved In Reproduction MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Response To Hormone Cellular Response To Hormone Stimulus Cellular Response To Steroid Hormone Stimulus Cellular Response To Organic Cyclic Compound Positive Regulation Of Transcription, DNA-templated Response To Steroid Hormone Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Lipid Intracellular Steroid Hormone Receptor Signaling Pathway Response To Lipid RNA Metabolic Process Maternal Process Involved In Female Pregnancy Regulation Of Gene Expression Gland Development Reproductive Structure Development Transcription, DNA-templated Reproductive System Development Cellular Nitrogen Compound Metabolic Process Gene Expression RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Mammary Gland Epithelium Development Response To Organic Substance Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Developmental Process Involved In Reproduction Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Reproductive Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Oxidoreductase Activity Mammary Gland Development Maternal Placenta Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
Tagcloud ?			androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 p44 pca promotion spliced suppressive switch switches tblr1 versions wdr77
Tagcloud (Difference) ?			androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 p44 pca promotion spliced suppressive switch switches tblr1 versions wdr77
Tagcloud (Intersection) ?