LRRC1 and CRMP1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LRRC1	CRMP1
Gene Name		leucine rich repeat containing 1	collapsin response mediator protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane	Cytoplasm Microtubule Organizing Center Spindle Cytosol Dendrite Neuronal Cell Body
	Molecular Function		Protein Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides
	Biological Process		Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance
Pathways			Axon guidance Semaphorin interactions CRMPs in Sema3A signaling
Drugs
Diseases
GWAS			Blood trace element (Zn levels) ( 23720494)
Protein-Protein Interactions		6 interactors: APP CRMP1 DLG1 DLG4 ERBB2IP KIAA1377	78 interactors: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DPYSL3 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LSM2 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1D1 ZAK ZNF24
Entrez ID		55227	1400
HPRD ID		06430	03913
Ensembl ID		ENSG00000137269	ENSG00000072832
Uniprot IDs		Q9BTT6	B3KT07 E9PD68 Q14194 Q96I11
PDB IDs			4B3Z
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Apical/basal Cell Polarity Cell Projection Morphogenesis Cell Part Morphogenesis Axon Guidance Cell Morphogenesis Receptor Localization To Synapse Cell Projection Organization Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Protein Localization To Synapse Neuron Projection Morphogenesis Establishment Or Maintenance Of Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Morphogenesis Involved In Differentiation Cortical Actin Cytoskeleton Organization Neuron Projection Development Cortical Cytoskeleton Organization Neuron Development Anatomical Structure Morphogenesis Receptor Clustering Neuron Differentiation Cytoskeleton Organization Nucleotide Phosphorylation Locomotion Neuromuscular Process Controlling Balance Synapse Assembly Movement Of Cell Or Subcellular Component Generation Of Neurons Neurogenesis Regulation Of Receptor Activity Cell Recognition Nucleobase-containing Small Molecule Metabolic Process Neuromuscular Process Cell Development Response To External Stimulus Basal Protein Localization Synaptic Growth At Neuromuscular Junction Learning Dendrite Development Cellular Component Assembly Cell Growth Collateral Sprouting In Absence Of Injury Synapse Organization Nervous System Development Collateral Sprouting Axon Midline Choice Point Recognition T Cell Cytokine Production Small Molecule Metabolic Process	Cell Death Death Developmental Process Apoptotic Process Programmed Cell Death Anatomical Structure Development Regulation Of Cellular Protein Metabolic Process Cell Differentiation Catabolic Process Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Cellular Response To Stress Regulation Of Cell Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Proteolysis Regulation Of Cysteine-type Endopeptidase Activity Response To Stimulus Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cellular Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Organic Substance Protein Homooligomerization Response To Stress Protein Polyubiquitination Positive Regulation Of Protein Complex Assembly Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Nitrogen Compound Metabolic Process Cellular Response To Stimulus Multicellular Organismal Development Cytoskeleton Organization Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Cellular Process Stress-activated MAPK Cascade Nervous System Development Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Cysteine-type Endopeptidase Activity System Development Positive Regulation Of Catalytic Activity Postreplication Repair Regulation Of Cellular Component Organization Protein Oligomerization Cellular Macromolecule Catabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Protein Complex Assembly Heterocycle Metabolic Process
Tagcloud ?			aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?			aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?