DCUN1D2 and UBE2F

Number of citations of the paper that reports this interaction (PMID 23201271)
5

Data Source:
BioGRID (pull down)

		DCUN1D2	UBE2F
Gene Name		DCN1, defective in cullin neddylation 1, domain containing 2	ubiquitin-conjugating enzyme E2F (putative)
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Gene Ontology Annotations	Cellular Component		Cytoplasm
	Molecular Function		Protein Binding ATP Binding Ligase Activity NEDD8 Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process		Protein Ubiquitination Protein Neddylation
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: APP UBE2F	9 interactors: CUL1 CUL5 DCUN1D1 DCUN1D2 NAE1 NEDD8 RNF34 RNF7 UBA3
Entrez ID		55208	140739
HPRD ID		12614	14812
Ensembl ID			ENSG00000184182
Uniprot IDs		Q6PH85	C9J212 H9KVB9 Q969M7
PDB IDs		4GAO	2EDI 3FN1 4GBA
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Protein Neddylation Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing Cholesterol Metabolic Process Adult Locomotory Behavior Positive Regulation Of Mitotic Cell Cycle Regulation Of Receptor Activity	Protein Neddylation Protein Modification By Small Protein Conjugation Apoptotic Process Cellular Protein Modification Process Programmed Cell Death Cell Death Death Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Intrinsic Apoptotic Signaling Pathway Protein Catabolic Process Cellular Protein Metabolic Process Proteolysis Mitotic Cell Cycle Cellular Macromolecule Catabolic Process Regulation Of Cell Cycle Apoptotic Signaling Pathway Protein Metabolic Process Negative Regulation Of Cell Cycle Cell Cycle Regulation Of Oxygen Metabolic Process Endomitotic Cell Cycle Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis Cell Cycle Arrest Mitotic Cell Cycle Process G1/S Transition Of Mitotic Cell Cycle Cellular Response To Cold Mitotic DNA Replication Checkpoint Catabolic Process Signal Transduction Negative Regulation Of Execution Phase Of Apoptosis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Signaling Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Communication DNA Replication Checkpoint Cell Cycle Process Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition Response To Redox State Cellular Response To Stimulus Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Execution Phase Of Apoptosis
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