DCUN1D2

Description		defective in cullin neddylation 1 domain containing 2
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding
	Biological Process	Protein Neddylation Regulation Of Protein Neddylation Positive Regulation Of Protein Neddylation
Pathways		Neddylation
Drugs
Diseases
GWAS		Birth weight ( 31043758) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494)
Interacting Genes		7 interacting genes: APP CAND1 CUL2 CUL3 MAP3K1 UBE2F UBE2M
Entrez ID		55208
HPRD ID		12614
Ensembl ID		ENSG00000150401
Uniprot IDs		Q6PH85
PDB IDs		4GAO
Enriched GO Terms of Interacting Partners?		Cullin-RING Ubiquitin Ligase Complex NEDD8 Conjugating Enzyme Activity NEDD8 Transferase Activity Protein Modification By Small Protein Conjugation Protein Metabolic Process Protein Modification Process Ubiquitin Ligase Complex Scaffold Activity Post-translational Protein Modification Protein Neddylation Postsynapse Ubiquitin-protein Transferase Activity Macromolecule Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cytosol Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Trophectodermal Cellular Morphogenesis Liver Morphogenesis Proteasomal Protein Catabolic Process SCF Complex Assembly PTB Domain Binding Positive Regulation Of Mitotic Cell Cycle Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Protein Catabolic Process At Postsynapse Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Regulation Of Postsynapse Organization Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Protein Ubiquitination Mitotic Cell Cycle Phase Transition POZ Domain Binding
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