RPRD1A and BCAR3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RPRD1A	BCAR3
Description		regulation of nuclear pre-mRNA domain containing 1A	BCAR3 adaptor protein, NSP family member
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Preinitiation Complex	Cytoplasm Focal Adhesion Membrane Anchoring Junction
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Identical Protein Binding RNA Polymerase II C-terminal Domain Binding	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding
	Biological Process	RNA Polymerase II Promoter Clearance MRNA 3'-end Processing	Lens Morphogenesis In Camera-type Eye Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Small GTPase-mediated Signal Transduction Positive Regulation Of Cell Population Proliferation Insulin Receptor Signaling Pathway Response To Xenobiotic Stimulus Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Endothelin Receptor Signaling Pathway
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Drug-induced torsades de pointes ( 24223155) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)	Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Liver fibrosis (total hepatic collagen content) ( 32953199) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)
Interacting Genes		13 interacting genes: BCAR3 FAM90A1 HGS KDM1A KPNA3 LONRF1 NXF1 PCNT RIOK2 SDCBP YWHAZ ZNF410 ZNF76	38 interacting genes: AGR3 AP1M1 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCDC57 CCL5 CST6 DKK3 DRC4 EGFR EPSTI1 ERBB2 ERBB3 ERBB4 ERRFI1 GAB1 GLCE GREB1 HOXC6 KIT KPNA1 MET MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP UBASH3A VPS45
Entrez ID		55197	8412
HPRD ID		10134	05268
Ensembl ID		ENSG00000141425	ENSG00000137936
Uniprot IDs		A0A0C4DGQ6 Q96P16	A0A384MTS3 B3KNL6 B3KP06 O75815
PDB IDs		4JXT 4NAC	3T6A
Enriched GO Terms of Interacting Partners?		Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Activity ERBB2 Signaling Pathway Receptor Complex Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Basal Plasma Membrane Protein Tyrosine Kinase Activity Regulation Of Peptidyl-tyrosine Phosphorylation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Epithelial Cell Proliferation Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Epithelial Cell Proliferation ERBB3:ERBB2 Complex Response To Epidermal Growth Factor Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Regulation Of Cell Population Proliferation Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Epithelial Cell Proliferation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Molecular Function Inhibitor Activity Positive Regulation Of Phosphate Metabolic Process Response To Growth Factor Regulation Of Protein Modification Process Protein Kinase Activity Positive Regulation Of Lymphocyte Migration Positive Chemotaxis ERBB2-EGFR Signaling Pathway Growth Factor Binding Regulation Of Primary Metabolic Process Cell Population Proliferation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Positive Regulation Of Mitotic Cell Cycle Regulation Of Protein Phosphorylation Basolateral Plasma Membrane Positive Regulation Of Cell Migration Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway
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