RPRD1A and RIOK2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RPRD1A	RIOK2
Gene Name		regulation of nuclear pre-mRNA domain containing 1A	RIO kinase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	DNA-directed RNA Polymerase II, Holoenzyme
	Molecular Function		Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Dephosphorylation Of RNA Polymerase II C-terminal Domain	Protein Phosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: BCAR3 KDM1A KPNA3 RIOK2 YWHAZ	6 interactors: APP CSNK2A1 RELA RPRD1A SMAD3 TSTA3
Entrez ID		55197	55781
HPRD ID		10134	10193
Ensembl ID		ENSG00000141425	ENSG00000058729
Uniprot IDs		Q96P16	Q9BVS4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Primitive Erythrocyte Differentiation Viral Penetration Into Host Nucleus Golgi Reassembly Histamine Secretion By Mast Cell Establishment Of Golgi Localization Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Golgi Inheritance Histone H3-K4 Demethylation Histamine Secretion Establishment Of Protein Localization To Organelle Positive Regulation Of Megakaryocyte Differentiation Histamine Transport Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Targeting Blood Coagulation Hemostasis Golgi Localization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Mast Cell Degranulation Response To Drug Protein Localization To Organelle Positive Regulation Of Erythrocyte Differentiation NLS-bearing Protein Import Into Nucleus Production Of Molecular Mediator Involved In Inflammatory Response Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Histone H3-K4 Methylation Mast Cell Mediated Immunity Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Hormone Biosynthetic Process Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Body Fluid Levels Lysosome Localization Intracellular Transport Of Virus Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Wound Healing Mast Cell Activation Lens Morphogenesis In Camera-type Eye Regulation Of Hematopoietic Progenitor Cell Differentiation Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Hormone Metabolic Process Histone Lysine Demethylation	Negative Regulation Of Protein Catabolic Process Positive Regulation Of Chondrocyte Differentiation Negative Regulation Of Protein Metabolic Process Positive Regulation Of Cartilage Development Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Endopeptidase Activity Regulation Of Protein Catabolic Process Regulation Of Peptidase Activity Regulation Of Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Regulation Of Chondrocyte Differentiation Regulation Of Cartilage Development Positive Regulation Of Transforming Growth Factor Beta3 Production Acetaldehyde Metabolic Process Regulation Of Growth Regulation Of Proteolysis Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Positive Regulation Of Schwann Cell Differentiation 'de Novo' GDP-L-fucose Biosynthetic Process Positive Regulation Of Peptidase Activity Liver Development Positive Regulation Of Wnt Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Schwann Cell Differentiation Evasion Or Tolerance Of Host Defenses By Virus GDP-L-fucose Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Development Regulation Of Protein Metabolic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Response To Cobalamin Dephosphorylation Of RNA Polymerase II C-terminal Domain Regulation Of Transcription, DNA-templated Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Apoptotic Process Intracellular Receptor Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Programmed Cell Death Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle Regulation Of Cysteine-type Endopeptidase Activity Regulation Of RNA Metabolic Process Regulation Of Extracellular Matrix Assembly Collateral Sprouting Axon Midline Choice Point Recognition Apoptotic Process
Tagcloud ?			checkpoint chemosensitivity creates drive drives drosophila exit feedforward glial glioblastoma glioblastomas imply incurable kinome maintains melanogaster neoplastic oncogenesis opportunities orthologs overexpressed pi3k riok1 rpl11 rtk screen screens uncovered
Tagcloud (Difference) ?			checkpoint chemosensitivity creates drive drives drosophila exit feedforward glial glioblastoma glioblastomas imply incurable kinome maintains melanogaster neoplastic oncogenesis opportunities orthologs overexpressed pi3k riok1 rpl11 rtk screen screens uncovered
Tagcloud (Intersection) ?