CEP192 and CIP2A

Number of citations of the paper that reports this interaction (PubMedID 25833693)
0

Data Source:
BioGRID (two hybrid)

		CEP192	CIP2A
Description		centrosomal protein 192	cellular inhibitor of PP2A
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GO Annotations	Cellular Component	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Procentriole Procentriole Replication Complex	Chromosome Cytoplasm Centrosome Cytosol Plasma Membrane Ciliary Basal Body
	Molecular Function	Protein Binding Phosphatase Binding	Protein Phosphatase Inhibitor Activity Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Centrosome Cycle Centriole Replication Response To Bacterium Centrosome Duplication Protein Localization To Centrosome Centrosome-templated Microtubule Nucleation Mitotic Spindle Assembly	DNA Damage Response Chromosome Organization Broken Chromosome Clustering
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) General cognitive ability ( 29844566)
Interacting Genes		5 interacting genes: CIP2A LINC00839 PPP1CA SHBG UBC	22 interacting genes: CDK1 CENPC CEP152 CEP192 CSPP1 GOLGA4 LAMB2 MYC NDC80 NEK2 PIK3R1 PPP2R5C PSMA1 PSMA3 RBM5 RNF2 SMC5 STUB1 SYNCRIP TOPBP1 UBR5 WWC3
Entrez ID		55125	57650
HPRD ID		10855	11151
Ensembl ID		ENSG00000101639	ENSG00000163507
Uniprot IDs		Q8TEP8	Q8TCG1
PDB IDs		4N7Z 6FVI 6W3J 7PTB 8GUW 8PR7	5UFL
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process Positive Regulation Of Termination Of DNA-templated Transcription Glycogen Granule Positive Regulation Of Termination Of RNA Polymerase II Transcription PTW/PP1 Phosphatase Complex RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Androgen Binding Mitochondrial Outer Membrane Meiotic Cytokinesis Formin-nucleated Actin Cable Assembly Parallel Actin Filament Bundle Assembly Establishment Of Meiotic Spindle Localization Polar Body Extrusion After Meiotic Divisions Cleavage Furrow Formation Actin Filament Network Formation Broken Chromosome Clustering	Nucleoplasm Chromosome Organization Centrosome Chromosome Chromosome, Centromeric Region Centrosome Duplication Procentriole DNA Damage Response Cytosol Positive Regulation Of Chromosome Organization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Chromosome Organization Positive Regulation Of Protein Import Into Nucleus Cytoplasm Microtubule Cytoskeleton Organization Involved In Mitosis Procentriole Replication Complex Chromosome Segregation Mitotic Cell Cycle Membraneless Organelle Assembly Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Process Proteasome Core Complex, Alpha-subunit Complex Cell Cycle Phase Transition Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Nuclear Body Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Catabolic Process Microtubule Organizing Center Organization Ubiquitin-ubiquitin Ligase Activity Kinetochore Organization Positive Regulation Of Intracellular Protein Transport Proteolysis Involved In Protein Catabolic Process Mitotic Spindle Organization Spindle Assembly Cell Division Positive Regulation Of Protein Localization To Nucleus Attachment Of Mitotic Spindle Microtubules To Kinetochore Proteasome Core Complex DNA Metabolic Process Protein Localization To Chromosome Intracellular Signal Transduction Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Cell Cycle Process Peptidyl-threonine Phosphorylation Macromolecule Metabolic Process Regulation Of Cell Cycle PML Body
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