CIP2A and GOLGA4

Number of citations: 49 (PubMedID 34145035)
Data Source: BioGRID (two hybrid)

		CIP2A	GOLGA4
Name		cellular inhibitor of PP2A	golgin A4
Structure
GO Annotations	Cellular Component	Chromosome Cytoplasm Centrosome Cytosol Plasma Membrane Ciliary Basal Body	Golgi Membrane Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding Protein Homodimerization Activity Cadherin Binding	Protein Binding Small GTPase Binding GTPase Binding
	Biological Process	DNA Damage Response Chromosome Organization Broken Chromosome Clustering	Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Axon Extension Golgi Vesicle Transport
Pathways		None	Retrograde transport at the Trans-Golgi-Network Signaling by membrane-tethered fusions of PDGFRA or PDGFRB
GWAS		No GWAS studies recorded	Autism spectrum disorder or schizophrenia ( 28540026 ) Pulse pressure ( 30578418 ) Subjective response to lithium treatment ( 26503763 )
Novel Interactors		2 novel interactors: ATIC CSNK2B	1 novel interactors: CDK6
Interacting Genes		22 interacting genes: CDK1 CENPC CEP152 CEP192 CSPP1 GOLGA4 LAMB2 MYC NDC80 NEK2 PIK3R1 PPP2R5C PSMA1 PSMA3 RBM5 RNF2 SMC5 STUB1 SYNCRIP TOPBP1 UBR5 WWC3	11 interacting genes: APP ARL1 ARL3 CIP2A EIF4ENIF1 MACF1 RAB6A RNF10 SERPINB5 TNIK TRAF3IP1
Entrez ID		57650	2803
HPRD ID		11151	03941
Ensembl ID		ENSG00000163507	ENSG00000144674
Uniprot IDs		Q8TCG1	A0A8V8TPI8 A0A8V8TQI6 A0A9L9PX25 C9J0Y3 H0Y6I0 Q13439 Q49A56
PDB IDs		5UFL	1R4A 1UPT
GO Terms Enriched among Interactors		Nucleoplasm Chromosome Organization Centrosome Chromosome Chromosome, Centromeric Region Centrosome Duplication Procentriole DNA Damage Response Cytosol Positive Regulation Of Chromosome Organization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Chromosome Organization Positive Regulation Of Protein Import Into Nucleus Cytoplasm Microtubule Cytoskeleton Organization Involved In Mitosis Procentriole Replication Complex Chromosome Segregation Mitotic Cell Cycle Membraneless Organelle Assembly Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Process Proteasome Core Complex, Alpha-subunit Complex Cell Cycle Phase Transition Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Nuclear Body Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Catabolic Process Microtubule Organizing Center Organization Ubiquitin-ubiquitin Ligase Activity Kinetochore Organization Positive Regulation Of Intracellular Protein Transport Proteolysis Involved In Protein Catabolic Process Mitotic Spindle Organization Spindle Assembly Cell Division Positive Regulation Of Protein Localization To Nucleus Attachment Of Mitotic Spindle Microtubules To Kinetochore Proteasome Core Complex DNA Metabolic Process Protein Localization To Chromosome Intracellular Signal Transduction Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Cell Cycle Process Peptidyl-threonine Phosphorylation Macromolecule Metabolic Process Regulation Of Cell Cycle PML Body	Endosome To Plasma Membrane Transport Vesicle Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Cellular Localization Trans-Golgi Network Membrane Ciliary Basal Body Intracellular Transport Microtubule-based Movement Protein Localization To Golgi Apparatus Establishment Of Localization In Cell Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cell Projection Organization Cytoplasm Organelle Organization Protein Transport Microtubule Binding Intraciliary Transport Cyclin D2-CDK6 Complex Peptidyl-cysteine Methylation Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Vesicle-mediated Transport Protein Localization To Organelle Centrosome Golgi Vesicle Transport Golgi To Plasma Membrane Transport Glial Cell Development Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Cell Projection Golgi Apparatus GTPase Activity Establishment Of Protein Localization Phospholipase D Activator Activity Protein Localization To Membrane Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Broken Chromosome Clustering Serine-type Endopeptidase Inhibitor Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Endothelin Production