CIP2A and CEP152

Number of citations of the paper that reports this interaction (PubMedID 25833693)
0

Data Source:
BioGRID (two hybrid)

		CIP2A	CEP152
Description		cellular inhibitor of PP2A	centrosomal protein 152
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GO Annotations	Cellular Component	Chromosome Cytoplasm Centrosome Cytosol Plasma Membrane Ciliary Basal Body	Pericentriolar Material Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Nuclear Body Ciliary Basal Body Deuterosome Procentriole Procentriole Replication Complex
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding Protein Homodimerization Activity Cadherin Binding	Protein Binding Protein Kinase Binding
	Biological Process	DNA Damage Response Chromosome Organization Broken Chromosome Clustering	Centriole Replication Cell Projection Organization Centrosome Duplication De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases			Seckel syndrome
GWAS			Diastolic blood pressure ( 30578418) Insomnia ( 23728906) Obesity-related traits ( 23251661)
Interacting Genes		22 interacting genes: CDK1 CENPC CEP152 CEP192 CSPP1 GOLGA4 LAMB2 MYC NDC80 NEK2 PIK3R1 PPP2R5C PSMA1 PSMA3 RBM5 RNF2 SMC5 STUB1 SYNCRIP TOPBP1 UBR5 WWC3	2 interacting genes: CIP2A EPB41L3
Entrez ID		57650	22995
HPRD ID		11151	16778
Ensembl ID		ENSG00000163507	ENSG00000103995
Uniprot IDs		Q8TCG1	O94986 Q3B7A2
PDB IDs		5UFL	4N7V 6CSU 6CSV
Enriched GO Terms of Interacting Partners?		Nucleoplasm Chromosome Organization Centrosome Chromosome Chromosome, Centromeric Region Centrosome Duplication Procentriole DNA Damage Response Cytosol Positive Regulation Of Chromosome Organization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Chromosome Organization Positive Regulation Of Protein Import Into Nucleus Cytoplasm Microtubule Cytoskeleton Organization Involved In Mitosis Procentriole Replication Complex Chromosome Segregation Mitotic Cell Cycle Membraneless Organelle Assembly Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Process Proteasome Core Complex, Alpha-subunit Complex Cell Cycle Phase Transition Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Nuclear Body Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Catabolic Process Microtubule Organizing Center Organization Ubiquitin-ubiquitin Ligase Activity Kinetochore Organization Positive Regulation Of Intracellular Protein Transport Proteolysis Involved In Protein Catabolic Process Mitotic Spindle Organization Spindle Assembly Cell Division Positive Regulation Of Protein Localization To Nucleus Attachment Of Mitotic Spindle Microtubules To Kinetochore Proteasome Core Complex DNA Metabolic Process Protein Localization To Chromosome Intracellular Signal Transduction Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Cell Cycle Process Peptidyl-threonine Phosphorylation Macromolecule Metabolic Process Regulation Of Cell Cycle PML Body	Protein Localization To Paranode Region Of Axon Ciliary Basal Body Cytoskeletal Protein-membrane Anchor Activity Protein Localization To Juxtaparanode Region Of Axon Broken Chromosome Clustering Paranodal Junction Assembly Paranode Region Of Axon Juxtaparanode Region Of Axon Axolemma Protein Localization To Axon Myelin Maintenance Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Cortical Actin Cytoskeleton Organization Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Synapse Cortical Cytoskeleton Organization Protein Phosphatase Inhibitor Activity Cytoskeletal Protein Binding
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