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MED19 and MED27
Number of citations of the paper that reports this interaction (PMID
21729782
)
60
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro)
MED19
MED27
Gene Name
mediator complex subunit 19
mediator complex subunit 27
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Mediator Complex
Nucleus
Nucleoplasm
Transcription Factor Complex
Nucleolus
Cytoplasm
Mediator Complex
Molecular Function
RNA Polymerase II Transcription Cofactor Activity
Protein Binding
Transcription Coactivator Activity
Protein Binding
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Stem Cell Maintenance
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions
11 interactors:
APP
DCK
DHRS7B
MED17
MED27
MED31
MED8
MED9
MSX1
NFKBIA
RADIL
9 interactors:
AFP
ARFGAP1
MED19
MED22
MED30
MED8
MED9
RBPJ
SOX5
Entrez ID
219541
9442
HPRD ID
17477
05438
Ensembl ID
ENSG00000156603
ENSG00000160563
Uniprot IDs
A0JLT2
Q6P2C8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Negative Regulation Of Cell Differentiation
Intracellular Receptor Signaling Pathway
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Stem Cell Development
Regulation Of Binding
Negative Regulation Of DNA Binding
Transcription, DNA-templated
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Gene Expression
Regulation Of Gene Expression
RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Stem Cell Differentiation
Cellular Nitrogen Compound Metabolic Process
Regulation Of Cell Differentiation
Nitrogen Compound Metabolic Process
Regulation Of DNA Binding
Cell Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway
Synaptic Growth At Neuromuscular Junction
Negative Regulation Of Binding
Collateral Sprouting In Absence Of Injury
Positive Regulation Of Mesenchymal Cell Apoptotic Process
Embryonic Nail Plate Morphogenesis
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Activation Of Meiosis
Biosynthetic Process
Stem Cell Maintenance
Collateral Sprouting
BMP Signaling Pathway Involved In Heart Development
Axon Midline Choice Point Recognition
Positive Regulation Of Transcription, DNA-templated
Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Cytoplasmic Sequestering Of NF-kappaB
Protein Localization To Nucleus
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Timing Of Cell Differentiation
Regulation Of Development, Heterochronic
RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
DNA-templated Transcription, Initiation
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Epidermal Cell Fate Specification
Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment
Positive Regulation Of Ephrin Receptor Signaling Pathway
Arterial Endothelial Cell Fate Commitment
Cellular Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Regulation Of Metabolic Process
Blood Vessel Lumenization
Blood Vessel Endothelial Cell Fate Specification
Nitrogen Compound Metabolic Process
Protein Secretion
Endothelial Cell Fate Specification
Stem Cell Maintenance
Clara Cell Differentiation
Positive Regulation Of Mesenchymal Stem Cell Differentiation
Interleukin-4 Secretion
Positive Regulation Of Transcription Of Notch Receptor Target
Regulation Of Cellular Process
Hair Follicle Maturation
Regulation Of Timing Of Neuron Differentiation
Auditory Receptor Cell Fate Commitment
Dorsal Aorta Morphogenesis
Arterial Endothelial Cell Differentiation
Regulation Of Mesenchymal Stem Cell Differentiation
Dorsal Aorta Development
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation
Endocardium Morphogenesis
Endothelial Tube Morphogenesis
Tagcloud
?
adp
b1
cyclin
downregulated
enneking
iib
iiib
ki67
knockdown
mediator
multimodal
nearly
nude
oncogene
oncogenes
os
osteosarcoma
parp
pcna
proliferating
remarkably
ribose
saos
simultaneously
spreading
tumour
tumourigenesis
u2os
xenograft
Tagcloud (Difference)
?
adp
b1
cyclin
downregulated
enneking
iib
iiib
ki67
knockdown
mediator
multimodal
nearly
nude
oncogene
oncogenes
os
osteosarcoma
parp
pcna
proliferating
remarkably
ribose
saos
simultaneously
spreading
tumour
tumourigenesis
u2os
xenograft
Tagcloud (Intersection)
?