CCDC186 and DUSP23

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CCDC186	DUSP23
Gene Name		coiled-coil domain containing 186	dual specificity phosphatase 23
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytosol Extracellular Vesicular Exosome
	Molecular Function		Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity
	Biological Process		Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS			C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Protein-Protein Interactions		2 interactors: DUSP23 PLEKHA5	24 interactors: ASB13 CCDC186 DBI DBN1 DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 KIAA1377 MKRN1 MRPL20 MTFR1 NIF3L1 PRDX4 RPL8 RUFY2 SHC1 SMPD1 TMOD3 TUBA1A ZNF746
Entrez ID		55088	54935
HPRD ID		16576	07908
Ensembl ID		ENSG00000165813	ENSG00000158716
Uniprot IDs		Q7Z3E2	Q9BVJ7
PDB IDs			2IMG 4ERC
Enriched GO Terms of Interacting Partners?			Cellular Metabolic Process Organelle Organization Regulation Of Gene Expression By Genetic Imprinting Gene Expression Genetic Imprinting Positive Regulation Of Histone Methylation Negative Regulation Of Male Germ Cell Proliferation Regulation Of Histone Methylation Positive Regulation Of Protein Modification Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Positive Regulation Of Histone Modification Negative Regulation Of Gene Expression, Epigenetic Cellular Nitrogen Compound Metabolic Process Regulation Of Male Germ Cell Proliferation Dihydrobiopterin Metabolic Process Cell Communication By Chemical Coupling S-adenosylmethioninamine Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Cytoskeleton Organization
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