IFT57 and YAF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IFT57	YAF2
Description		intraflagellar transport 57	YY1 associated factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centrosome Microtubule Organizing Center Cytoskeleton Cilium Axoneme Intraciliary Transport Particle B Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Dendrite Terminus Ciliary Tip Ciliary Base	Nucleus Nucleoplasm Cytosol
	Molecular Function	DNA Binding Protein Binding	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Neural Tube Closure Heart Looping Apoptotic Process Smoothened Signaling Pathway Negative Regulation Of Keratinocyte Proliferation Intraciliary Anterograde Transport Intraciliary Transport Regulation Of Apoptotic Process Keratinocyte Proliferation Motile Cilium Assembly Cilium Assembly Left/right Pattern Formation Non-motile Cilium Assembly	Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Bipolar disorder ( 31043756) Regular attendance at a religious group ( 29970889)	Refractive error ( 32231278)
Interacting Genes		8 interacting genes: EXOC5 HIP1 IFT20 SKA2 UBXN10 WASHC1 YAF2 ZDHHC17	28 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 PTEN SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42
Entrez ID		55081	10138
HPRD ID		09430	09606
Ensembl ID		ENSG00000114446	ENSG00000015153
Uniprot IDs		Q9NWB7	B4DJQ9 G3V212 Q8IY57
PDB IDs			2D9G
Enriched GO Terms of Interacting Partners?		Protein Transport Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Establishment Of Protein Localization Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Intracellular Protein Localization Cytoplasmic Vesicle Exocyst Cellular Localization Establishment Of Localization In Cell Intraciliary Transport Particle B Clathrin Coat Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Establishment Of Planar Polarity Organelle Assembly Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Intracellular Transport Centriole Cytoplasmic Vesicle Membrane Positive Regulation Of Cilium Assembly Cytoskeleton Regulation Of Cell Projection Assembly Establishment Of Spindle Orientation Phosphate:proton Symporter Activity Mitochondrial Phosphate Ion Transmembrane Transport TERT-RMRP Complex Template-free RNA Nucleotidyltransferase Positive Regulation Of Transdifferentiation RNA-directed RNA Polymerase Complex SiRNA Transcription Perforant Pathway To Dendrate Granule Cell Synapse Establishment Of Spindle Localization Spindle Localization Cilium Assembly Cellular Component Assembly Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Presynaptic Endocytic Zone Membrane Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Hair Cycle Telomerase Catalytic Core Complex Cilium Organization Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Opsin Transport Intraciliary Transport Particle Regulation Of Receptor Internalization Vesicle-mediated Transport Regulation Of Cellular Component Organization Clathrin-coated Vesicle Autophagosome	Nucleoplasm Regulation Of MiRNA Transcription Positive Regulation Of Telomere Maintenance Protein Tag Activity Regulation Of Synaptic Vesicle Clustering Regulation Of DNA Strand Elongation Ino80 Complex Positive Regulation Of Telomere Maintenance In Response To DNA Damage Chromatin Organization Regulation Of MiRNA Metabolic Process
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