IFT57 and UBXN10

Number of citations of the paper that reports this interaction (PubMedID 26389662)
53

Data Source:
BioGRID (pull down)

		IFT57	UBXN10
Description		intraflagellar transport 57	UBX domain protein 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centrosome Microtubule Organizing Center Cytoskeleton Cilium Axoneme Intraciliary Transport Particle B Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Dendrite Terminus Ciliary Tip Ciliary Base	Endoplasmic Reticulum Cilium Intraciliary Transport Particle B Cell Projection
	Molecular Function	DNA Binding Protein Binding	Protein Binding Ubiquitin Binding
	Biological Process	Neural Tube Closure Heart Looping Apoptotic Process Smoothened Signaling Pathway Negative Regulation Of Keratinocyte Proliferation Intraciliary Anterograde Transport Intraciliary Transport Regulation Of Apoptotic Process Keratinocyte Proliferation Motile Cilium Assembly Cilium Assembly Left/right Pattern Formation Non-motile Cilium Assembly	Cell Projection Organization ERAD Pathway Cilium Assembly
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Bipolar disorder ( 31043756) Regular attendance at a religious group ( 29970889)	Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)
Interacting Genes		8 interacting genes: EXOC5 HIP1 IFT20 SKA2 UBXN10 WASHC1 YAF2 ZDHHC17	13 interacting genes: APP CLUAP1 IFT46 IFT57 IFT70A IFT70B IFT80 LRRK2 PRMT6 TRAF3IP1 UBXN6 UNC13A VCP
Entrez ID		55081	127733
HPRD ID		09430	18255
Ensembl ID		ENSG00000114446	ENSG00000162543
Uniprot IDs		Q9NWB7	Q96LJ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Transport Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Establishment Of Protein Localization Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Intracellular Protein Localization Cytoplasmic Vesicle Exocyst Cellular Localization Establishment Of Localization In Cell Intraciliary Transport Particle B Clathrin Coat Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Establishment Of Planar Polarity Organelle Assembly Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Intracellular Transport Centriole Cytoplasmic Vesicle Membrane Positive Regulation Of Cilium Assembly Cytoskeleton Regulation Of Cell Projection Assembly Establishment Of Spindle Orientation Phosphate:proton Symporter Activity Mitochondrial Phosphate Ion Transmembrane Transport TERT-RMRP Complex Template-free RNA Nucleotidyltransferase Positive Regulation Of Transdifferentiation RNA-directed RNA Polymerase Complex SiRNA Transcription Perforant Pathway To Dendrate Granule Cell Synapse Establishment Of Spindle Localization Spindle Localization Cilium Assembly Cellular Component Assembly Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Presynaptic Endocytic Zone Membrane Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Hair Cycle Telomerase Catalytic Core Complex Cilium Organization Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Opsin Transport Intraciliary Transport Particle Regulation Of Receptor Internalization Vesicle-mediated Transport Regulation Of Cellular Component Organization Clathrin-coated Vesicle Autophagosome	Intraciliary Transport Particle B Intraciliary Anterograde Transport Intraciliary Transport Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Ciliary Tip Microtubule-based Transport Establishment Of Localization In Cell Intracellular Transport Microtubule-based Movement Cellular Localization Microtubule-based Process Cell Projection Cell Projection Organization Cilium Assembly Cilium Organization Ciliary Basal Body Cilium Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Smoothened Signaling Pathway Cellular Component Assembly Plasma Membrane Bounded Cell Projection Organization Intraciliary Transport Particle B Binding Centrosome Ciliary Base Organelle Assembly Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Cellular Response To Manganese Ion Left/right Pattern Formation Response To Manganese Ion Microtubule Organizing Center Golgi-associated Vesicle Regulation Of Wnt Signaling Pathway Cellular Response To Catecholamine Stimulus Syntaxin-1 Binding Response To Catecholamine Negative Regulation Of Keratinocyte Proliferation Regulation Of Proteolysis Organelle Organization Keratinocyte Proliferation Regulation Of Ubiquitin-dependent Protein Catabolic Process Axonemal Microtubule Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of ATP Metabolic Process Anatomical Structure Morphogenesis Terminal Bouton Cytoskeleton Endosome Transport Via Multivesicular Body Sorting Pathway
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