PPP1CB and PPP1R9A

Number of citations of the paper that reports this interaction (PubMedID 15016827)
0

Data Source:
BioGRID (far western blotting)

		PPP1CB	PPP1R9A
Description		protein phosphatase 1 catalytic subunit beta	protein phosphatase 1 regulatory subunit 9A
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Focal Adhesion Extracellular Exosome PTW/PP1 Phosphatase Complex	Cytoplasm Cytoskeleton Postsynaptic Density Actin Cytoskeleton Filopodium Dendrite Cortical Actin Cytoskeleton Neuron Projection Dendritic Spine Synapse Plasma Membrane Bounded Cell Projection
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Hydrolase Activity Phosphatase Activity Myosin Phosphatase Activity Protein Kinase Binding Metal Ion Binding Myosin-light-chain-phosphatase Activity	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	MAPK Cascade Glycogen Metabolic Process Protein Dephosphorylation Regulation Of Cell Adhesion Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Rhythmic Process Cell Division	Actin Filament Organization Nervous System Development Calcium-mediated Signaling Cell Differentiation Neuron Projection Development Modulation Of Chemical Synaptic Transmission
Pathways		Triglyceride catabolism Downregulation of TGF-beta receptor signaling Regulation of PLK1 Activity at G2/M Transition RHO GTPases activate PKNs RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs RAF activation SHOC2 M1731 mutant abolishes MRAS complex function Gain-of-function MRAS complexes activate RAF signaling Maturation of hRSV A proteins Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
Drugs
Diseases
GWAS		Body mass index ( 25673413) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Excessive sweating ( 29895819) Heel bone mineral density ( 28869591 30598549) Pre-treatment viral load in HIV-1 infection ( 31219150) Pure non-grapefruit juice consumption ( 31046077)	Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Waist circumference ( 28552196)
Interacting Genes		46 interacting genes: ACTN2 AURKA BRCA1 C14orf180 CHCHD3 CLK1 CLOCK CSNK2B CSRNP2 CYSRT1 DELEC1 FBXO7 H3-3A H3C1 HOXA2 KANK2 KIF23 LMTK2 MAPT MEOX2 NONO PHACTR3 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R16A PPP1R27 PPP1R2B PPP1R2C PPP1R3A PPP1R3B PPP1R3C PPP1R7 PPP1R9A PPP2R5C PRKAR2A PTK2 RB1 RORC SPATC1L TLX1 TP53BP2 UBAC1 WBP11 ZFYVE9	11 interacting genes: ACTG1 MECOM PPP1CA PPP1CB PPP1CC PPP1R2 PPP1R9B PRKAR1B RPS6KA1 RPS6KB1 TGOLN2
Entrez ID		5500	55607
HPRD ID		11792	16000
Ensembl ID		ENSG00000213639	ENSG00000158528
Uniprot IDs		P62140 V9HW04	A4D1I0 B7ZLX4 Q9ULJ8
PDB IDs			1WF8
Enriched GO Terms of Interacting Partners?		Myosin Phosphatase Regulator Activity Protein Phosphatase Inhibitor Activity Phosphatase Regulator Activity Protein Phosphatase 1 Binding Glycogen Binding Protein Phosphatase Regulator Activity Protein Phosphatase Type 1 Complex Phosphatase Binding Enzyme Inhibitor Activity Glycogen Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process Regulation Of Glycogen Biosynthetic Process Stress Fiber Regulation Of Centromere Complex Assembly Regulation Of Glycogen Metabolic Process Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Protein Kinase Binding Centrosome Cycle Negative Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Chromatin Cell Projection Organization Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle A Band Segment Specification Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Cell Cycle Process	PTW/PP1 Phosphatase Complex Glycogen Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock Energy Derivation By Oxidation Of Organic Compounds Circadian Regulation Of Gene Expression Phosphatase Activity Glutamatergic Synapse Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Protein Phosphatase Type 1 Complex Generation Of Precursor Metabolites And Energy Regulation Of Circadian Rhythm Dephosphorylation Circadian Rhythm Carbohydrate Metabolic Process Regulation Of Translation In Response To Stress Phosphoprotein Phosphatase Activity Dendritic Spine Protein Serine/threonine/tyrosine Kinase Activity Synapse Chromosome, Telomeric Region Postsynapse Intracellular Signal Transduction Protein Phosphatase Inhibitor Activity Rhythmic Process Basal Body Patch Nucleoplasm Myosin-light-chain-phosphatase Activity Positive Regulation Of Protein Localization To Actin Cortical Patch Dendritic Spine Neck Cytoplasmic Side Of Dendritic Spine Plasma Membrane TORC1 Signaling Cellular Response To Type II Interferon Regulation Of Signal Transduction Phosphate-containing Compound Metabolic Process Response To Light Stimulus Negative Regulation Of Intracellular Signal Transduction Protein-containing Complex Binding RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity TOR Signaling Negative Regulation Of TOR Signaling Intracellular Signaling Cassette Schaffer Collateral - CA1 Synapse Response To Type II Interferon Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled
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