EPN3 and DAZAP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EPN3	DAZAP2
Description		epsin 3	DAZ associated protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Plasma Membrane Clathrin-coated Pit Cytoplasmic Side Of Plasma Membrane Clathrin Vesicle Coat Clathrin-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Cytoplasm Cytoplasmic Stress Granule Nuclear Body Nuclear Speck Protein-containing Complex
	Molecular Function	Protein Binding Phospholipid Binding Lipid Binding Clathrin Binding EH Domain Binding	P53 Binding Transcription Coactivator Activity Protein Binding Receptor Tyrosine Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity WW Domain Binding Protein Serine/threonine Kinase Binding DNA-binding Transcription Factor Binding
	Biological Process	Endocytosis	Protein Destabilization Stress Granule Assembly Positive Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Hip index ( 34021172)
Interacting Genes		11 interacting genes: DAZAP2 FAM168A LAPTM5 LITAF NTAQ1 RNF11 RNF8 RPS27A TRIM26 UBA52 UBC	168 interacting genes: AATF ACOT7 AOC1 ARID5A ATXN1 ATXN1L BAG3 BATF2 BHLHE40 C1orf94 CALCOCO2 CAMK2A CAPN15 CCDC120 CDK4 CELF5 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 DESI1 DTX2 EPN1 EPN2 EPN3 ESRP1 EXD3 FAM168A FAM83A FBN3 FOXH1 GGA3 GPS2 GPSM1 HEY1 HGS HIP1 HIPK2 INCA1 KLHL42 KRTAP19-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 LGALS9 LITAF LMO2 MAGED1 MAPK1IP1L MED31 MINDY1 MINDY3 MTURN MYEOV MYOZ3 NDUFA5 NEDD4 NEDD4L NOC4L NOTCH1 OPTN OTUB2 OTUD7B OTULIN PATZ1 PDIK1L PEF1 PITX2 PLEKHB2 PLEKHF2 PLSCR1 PLSCR4 POGZ POLI PROP1 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E PRR34 RABGEF1 RAD18 RAD23A RAMAC RBFOX1 RBFOX2 RBM11 RBM24 RBM43 RBPMS RHOXF2 RNF115 RNF208 RNF44 ROR2 RPS27A RUNX1 SEPTIN2 SIAH1 SMAP2 SMURF2 SNRPC SOX10 SOX6 SPMIP9 SQSTM1 STAM2 STAT6 TAX1BP1 TBX6 TCF7L2 TENT5B TENT5C TFG TIAL1 TLE1 TLE5 TNIP1 TNIP3 TOLLIP TOM1 TP53 UBA52 UBAC1 UBAP2 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBE2E3 UBE2V1 UBE3A UBQLN1 UBQLN2 UBQLN4 UBXN6 UBXN7 USP13 USP5 VENTX VEZF1 VHLL VPS37C WDR73 WWOX WWP1 YOD1 ZBTB32 ZC3H10 ZFAND2A ZFAND2B ZFYVE9 ZNF34 ZNF581
Entrez ID		55040	9802
HPRD ID		06272	08463
Ensembl ID		ENSG00000049283	ENSG00000183283
Uniprot IDs		Q9H201	Q15038
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Binding Protein Tag Activity Modification-dependent Protein Catabolic Process Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Post-translational Protein Modification Endocytic Vesicle Membrane Protein Modification Process Macromolecule Catabolic Process Endosome Membrane Regulation Of Non-canonical NF-kappaB Signal Transduction Proteolysis WW Domain Binding Vesicle Mitochondrial Outer Membrane Regulation Of Macrophage Cytokine Production Catabolic Process Induction Of Programmed Cell Death Negative Regulation Of Pre-B Cell Receptor Expression Positive Regulation Of Lysosomal Membrane Permeability Protein-N-terminal Glutamine Amidohydrolase Activity Protein Metabolic Process Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Protein Autoubiquitination Ubiquitin Protein Ligase Activity Regulation Of Lysosomal Membrane Permeability Cytoplasmic Side Of Late Endosome Membrane Positive Regulation Of Base-excision Repair Protein-N-terminal Asparagine Amidohydrolase Activity Lysosomal Membrane Cytosolic Ribosome Negative Regulation Of Autophagic Cell Death Ubiquitin Ligase Complex Cytoplasmic Side Of Early Endosome Membrane Regulation Of Base-excision Repair Cytoplasmic Translation Regulation Of Cytokine Production Involved In Immune Response Nucleus Positive Regulation Of DNA Repair Structural Constituent Of Ribosome Response To Insecticide Zinc Ion Binding Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Receptor Catabolic Process	Protein Binding Polyubiquitin Modification-dependent Protein Binding Post-translational Protein Modification Ubiquitin Binding Nucleus Protein Ubiquitination Protein Modification By Small Protein Conjugation Nucleoplasm Modification-dependent Protein Catabolic Process Proteolysis Proteolysis Involved In Protein Catabolic Process Autophagy Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process K48-linked Deubiquitinase Activity Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Catabolic Process Cytoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin-dependent Protein Catabolic Process Cysteine-type Deubiquitinase Activity Positive Regulation Of Metabolic Process Macroautophagy Protein K48-linked Deubiquitination Negative Regulation Of Signal Transduction Cysteine-type Peptidase Activity Protein Modification Process Ubiquitin-protein Transferase Activity Protein K63-linked Ubiquitination Negative Regulation Of Transcription By RNA Polymerase II Ubiquitin Protein Ligase Binding Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Protein Tag Activity Protein Metabolic Process Identical Protein Binding Cytosol Autophagosome Negative Regulation Of DNA-templated Transcription Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Modification By Small Protein Removal Clathrin Binding Negative Regulation Of RNA Biosynthetic Process Regulation Of Macroautophagy Establishment Of Protein Localization To Vacuole
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