TTC38 and PFDN1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		TTC38	PFDN1
Description		tetratricopeptide repeat domain 38	prefoldin subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Exosome	Cytoplasm Prefoldin Complex Protein-containing Complex
	Molecular Function	Protein Binding	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process		Protein Folding Negative Regulation Of Amyloid Fibril Formation
Pathways			Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Urinary metabolite levels in chronic kidney disease ( 31959995)	Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)
Interacting Genes		2 interacting genes: PFDN1 TK1	55 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEBPA CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235
Entrez ID		55020	5201
HPRD ID		07943	05357
Ensembl ID		ENSG00000075234	ENSG00000113068
Uniprot IDs		Q5R3I4	O60925
PDB IDs			6NR8 6NR9 6NRB 6NRC 6NRD 7WU7
Enriched GO Terms of Interacting Partners?		Prefoldin Complex DNA Synthesis Involved In Mitotic DNA Replication Thymidine Metabolic Process Thymidine Biosynthetic Process Thymidine Kinase Activity Deoxyribonucleoside Monophosphate Biosynthetic Process TORC2 Complex Pyrimidine Nucleoside Metabolic Process Negative Regulation Of Amyloid Fibril Formation TORC2 Signaling Regulation Of Amyloid Fibril Formation Pyrimidine-containing Compound Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Nucleoside Metabolic Process	Positive Regulation Of Microtubule Nucleation Structural Constituent Of Cytoskeleton Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Microtubule Nucleation Nuclear Matrix Positive Regulation Of DNA Recombination NuA4 Histone Acetyltransferase Complex Regulation Of Cell Cycle Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Microtubule Polymerization Positive Regulation Of Double-strand Break Repair Intracellular Protein Localization Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cytoskeleton Organization Regulation Of Supramolecular Fiber Organization Glutamate Receptor Binding Regulation Of Cellular Component Organization
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