EXD3 and DAZAP2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		EXD3	DAZAP2
Gene Name		exonuclease 3-5 domain containing 3	DAZ associated protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Nucleic Acid Binding Protein Binding 3'-5' Exonuclease Activity Metal Ion Binding	Protein Binding WW Domain Binding
	Biological Process	Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: DAZAP2 PLSCR1	86 interactors: AATF ARID5A ATXN1 ATXN1L BAG3 BATF2 C1orf94 CALCOCO2 CCDC120 CDK4 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 EPN1 EXD3 FAM168A FAM46B FAM46C FBN3 GPSM1 HGS HIP1 KRTAP19-5 KRTAP8-1 LASP1 LMO2 MED31 NDUFA5 NEDD4 NEDD4L NOC4L OPTN OTULIN PEF1 PLEKHB2 PLSCR1 POGZ POLI PRR20A RABGEF1 RBFOX1 RBFOX2 RBPMS RHOXF2 RNF115 RNF208 ROR2 RPS27A SEPT2 SMAP2 SMURF2 SOX6 SQSTM1 STAM2 STAT6 TAX1BP1 TCF7L2 TEX37 TLE1 TNIP3 TOLLIP UBA52 UBAC1 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBQLN4 USP5 VHLL VPS37C WDR73 WWP1 ZC3H10 ZFAND2B ZFYVE9 ZNF34 ZNF581
Entrez ID		54932	9802
HPRD ID		07906	08463
Ensembl ID		ENSG00000187609	ENSG00000183283
Uniprot IDs		Q8N9H8	E9PB45 Q15038
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Phosphatidylserine Biosynthetic Process Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Phospholipid Scrambling Response To Interferon-beta Phosphatidylserine Metabolic Process Positive Regulation Of ATPase Activity Regulation Of Mast Cell Activation Acute-phase Response Regulation Of ATPase Activity Negative Regulation Of Viral Genome Replication Regulation Of Membrane Lipid Distribution Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Acute Inflammatory Response Phospholipid Transport Regulation Of Viral Process Defense Response To Virus Positive Regulation Of Innate Immune Response Platelet Activation Glycerophospholipid Biosynthetic Process Plasma Membrane Organization Phospholipid Biosynthetic Process Regulation Of Innate Immune Response Cellular Modified Amino Acid Metabolic Process Response To Virus	Negative Regulation Of Signal Transduction Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Viral Protein Processing Regulation Of ERBB Signaling Pathway Protein Ubiquitination Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Polyubiquitination Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Metabolic Process Response To Transforming Growth Factor Beta Virion Assembly Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Signaling Intracellular Transport Of Virus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway RNA Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Protein Metabolic Process RNA Biosynthetic Process Endosomal Transport Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Type I Interferon Production Transforming Growth Factor Beta Receptor Signaling Pathway Modification-dependent Protein Catabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
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