EXD3

Description		exonuclease 3'-5' domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Nucleic Acid Binding Nuclease Activity Exonuclease Activity Protein Binding 3'-5' Exonuclease Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process
Pathways
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Age at first sexual intercourse ( 34211149) Appendicular lean mass ( 33097823) Chronotype ( 27494321 30696823) Loneliness ( 27629369) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Multisite chronic pain ( 31194737 33830993) Platelet distribution width ( 32888494)
Novel Interacting Genes		1 novel interacting genes: INPP5E
Interacting Genes		2 interacting genes: DAZAP2 PLSCR1
Entrez ID		54932
HPRD ID		07906
Ensembl ID		ENSG00000187609
Uniprot IDs		Q8N9H8
PDB IDs
Enriched GO Terms of Interacting Partners?		Glycerophospholipid Biosynthetic Process Phospholipid Biosynthetic Process Phosphatidylserine Biosynthetic Process Mercury Ion Binding Lead Ion Binding Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Phosphatidylinositol-4,5-bisphosphate Phosphatase Activity Negative Regulation Of Protein Localization To Cilium Glycerophospholipid Metabolic Process Response To Inositol Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Phospholipid Metabolic Process Glycerolipid Metabolic Process Phosphatidylinositol-3,5-bisphosphate 5-phosphatase Activity Inositol-polyphosphate 5-phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity CD4 Receptor Binding Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Regulation Of Protein Localization To Cilium Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Organophosphate Biosynthetic Process Phosphatidylserine Metabolic Process Regulation Of Mast Cell Activation Phospholipid Scramblase Activity Lipid Biosynthetic Process Response To Lead Ion Positive Regulation Of ATP-dependent Activity Mitogen-activated Protein Kinase Kinase Kinase Binding Negative Regulation Of Phagocytosis Plasma Membrane Phospholipid Scrambling Phosphatidylinositol-3-phosphate Biosynthetic Process WW Domain Binding Protein Serine/threonine Kinase Binding Phosphatidylinositol Dephosphorylation Plasma Membrane Bounded Cell Projection Organelle Assembly Epidermal Growth Factor Receptor Binding Regulation Of ATP-dependent Activity Positive Regulation Of Chromosome Separation Response To Interferon-beta Stress Granule Assembly Phospholipid Translocation Phospholipid Dephosphorylation Acute-phase Response Lipid Translocation Organophosphate Metabolic Process Regulation Of Membrane Lipid Distribution Negative Regulation Of Viral Genome Replication Phosphatidylinositol Phosphate Biosynthetic Process
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