SLU7 and PCBP2

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SLU7	PCBP2
Gene Name		SLU7 splicing factor homolog (S. cerevisiae)	poly(rC) binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane Nuclear Speck Small Nuclear Ribonucleoprotein Complex Intracellular Membrane-bounded Organelle Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Membrane Ribonucleoprotein Complex Extracellular Vesicular Exosome
	Molecular Function	Second Spliceosomal Transesterification Activity Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding	DNA Binding RNA Binding Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding Poly(A) RNA Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Intracellular Protein Transport Cellular Response To Heat	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression MRNA Metabolic Process Negative Regulation Of Type I Interferon Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Negative Regulation Of Defense Response To Virus Defense Response To Virus
Pathways			RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing Negative regulators of RIG-I/MDA5 signaling mRNA Splicing - Major Pathway Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: BAG2 CCDC85B CEP70 GOLGA2 GTF2I JMJD6 KDM1A KRT40 LZTS2 PCBP2 PPIG PPIL3 PRMT5 PRMT6 THAP1 WHSC1L1 ZCCHC10	25 interactors: BARD1 CASK CNBP FLNA HMGA1 HMGA2 HNRNPD HNRNPK HNRNPL NKAP PABPC1 PAXIP1 PCBP1 PRPF40A PTBP1 QKI SF3B2 SLU7 SNRPA SRSF3 SRSF7 WDR77 WDR83 YBX1 YBX3
Entrez ID		10569	5094
HPRD ID		12074	03129
Ensembl ID		ENSG00000164609	ENSG00000197111
Uniprot IDs		O95391	B4DXP5 F8VZX2 G3V0E8 Q15366
PDB IDs			2AXY 2JZX 2P2R 2PQU 2PY9
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression RNA Splicing Histone Modification Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Peptidyl-amino Acid Modification RNA Processing Cellular Nitrogen Compound Metabolic Process Histone H4-R3 Methylation Chromatin Modification Transcription, DNA-templated RNA Biosynthetic Process Peptidyl-arginine N-methylation Nitrogen Compound Metabolic Process Chromatin Organization Histone Methylation Histone Arginine Methylation Peptidyl-arginine Methylation MRNA Processing Protein Methylation Histone Demethylation Protein Demethylation MRNA Metabolic Process Chromosome Organization Cellular Protein Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Protein Binding Cellular Macromolecule Biosynthetic Process Histone H3-R2 Demethylation Histone H4-R3 Demethylation Regulation Of Primitive Erythrocyte Differentiation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Protein Folding Macromolecule Biosynthetic Process Demethylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Protein Peptidyl-prolyl Isomerization Histone H3-R2 Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Transition Between Slow And Fast Fiber Organelle Organization Negative Regulation Of Binding Cellular Protein Modification Process	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Gene Expression Posttranscriptional Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of RNA Metabolic Process Transcription, DNA-templated Oncogene-induced Cell Senescence Positive Regulation Of Macromolecule Biosynthetic Process Metabolic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of MRNA Processing MRNA Stabilization Regulation Of Nitrogen Compound Metabolic Process Senescence-associated Heterochromatin Focus Assembly Negative Regulation Of Gene Expression Positive Regulation Of Cellular Senescence Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Aging Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Translation Heterochromatin Assembly Biosynthetic Process MRNA 3'-end Processing Heterochromatin Organization Positive Regulation Of Cellular Metabolic Process Regulation Of MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Translation
Tagcloud ?			9b aip4 atg5 clue coronaviruses cov depended dynamin etiologic evade evades fission havoc hect illustrates localizes manipulates mavs mitochondria orf outbreak proteasomal sars signalosome traf traf3 triggering uncovered usurping
Tagcloud (Difference) ?			9b aip4 atg5 clue coronaviruses cov depended dynamin etiologic evade evades fission havoc hect illustrates localizes manipulates mavs mitochondria orf outbreak proteasomal sars signalosome traf traf3 triggering uncovered usurping
Tagcloud (Intersection) ?